A miniature dachshund aged 9 years and 7 months with a history of polyuria/polydipsia and depression was referred. General physical and neurological examinations revealed no obvious abnormalities. MRI of the brain revealed a large space-occupying lesion in the left frontal lobe. This was surgically removed and pathologically diagnosed as a primitive neuroectodermal tumor (PNET). Although the cl...

Primary cerebral neuroblastoma is a rare entity that has been classified within the broader category of primitive neuroectodermal tumors (PNET). We present a case of primary cerebral neuroblastoma that had invaded the dural sinuses and metastasized to the lungs at the time of diagnosis. MR imaging provided an excellent means of localizing the extent of the primary tumor as well as identifying c...

BACKGROUND AND PURPOSE Ependymoblastoma is a malignant embryonal tumor that develops in early childhood and has a dismal prognosis. Categorized by the World Health Organization as a subgroup of CNS-primitive neuroectodermal tumor, ependymoblastoma is histologically defined by "ependymoblastic rosettes." Because it is so rare, little is known about specific MR imaging characteristics of ependymo...

Primary primitive neuroectodermal tumors (PNETs) are extremely rare in the lung and especially in adult women. We describe a case of PNET of the lung with aggressive behavior in 31-year-old woman. Diagnosis was based on histopathological and immunohistochemical studies, and confirmed by molecular genetic analysis of chromosome rearrangements in the EWSR1 gene region. Clinical follow-up, post-mo...

After presenting for a routine screening exam, and 57-year-old man was diagnosed with an incidentaloma-a primitive neuroectodermal tumor (PNET) of the thymus. A member of the Ewing sarcoma family of tumors, a PNET is typically regarded as a malignancy of childhood and adolescence, usually occurring in the central nervous system. In the case at hand, our patient had an extremely unusual presenta...

BACKGROUND Ewing's family of tumors (EFT) comprises a broad spectrum of tumors composed of primitive committed cells with neuroectodermal capacity. The degree of neural differentiation within EFT, as measured with morphological features and expression of neural markers, delimits two members: Ewing's sarcoma (ES) and peripheral primitive neuroectodermal tumor (pPNET). Molecules such as c-kit and...

Pineal parenchymal tumor (PPT) cells usually show immunoreactivity for synaptophysin, neuron-specific enolase, neurofilament protein, class III beta-tubulin, tau protein, PGP9.5, chromogranin, serotonin, retinal S-antigen, and rhodopsin, but these markers are not specific for PPTs. Melatonin is produced and secreted mainly bypineal parenchymal cells; hydroxyindole-O-methyltransferase (HIOMT) ca...

Purpose: The aim of this study was to evaluate tne effect the risk group on clinical features disease, treatment strategies and especially survival in children with Non-Wilms’ renal tumors (NWRTs). 
 Materials Methods: Patients diagnosed NWRTs followed up treated between January 2012 2022 were included (n=29; 16 boys 13 girls). They categorized into high- low-risk groups based their histol...

Primitive  neuroectodermal  tumor  (PNET)  of  kidney  is  an  extremely  rare  renal  neoplasm  with only about fifty reported cases in literature.  Presumably,of neural crest origin, these tumors behave  aggressively  and  carry  a  poor prognosis.  We  report  a  case  of  22-year  old  female  patient complaining of left loin pain with recurrent hematuria for last 3 months. On clinical ex...

Ewing sarcoma-primitive neuroectodermal tumors (ES/PNETs) constitute a family of neoplasms characterized by a continuum of neuroectodermal differentiations. ES/PNET of the uterus is rare. There are 48 cases of ES/PNET of the uterus published in the literature as far as we know. We describe a case of Ewing sarcoma of the uterus occurring in a 17-year-old woman presenting with a two-month history...