We report a case of a 29-year-old man who presented with a distal humeral shaft fracture sustained by blunt trauma. Physicalexamination and nerve conduction study were consistent with injury to the median and radial nerves proximal to theelbow. The patient underwent open reduction and internal fixation of the humeral shaft fracture with neurolysis of the medianand radial nerves. Repeat electrom...

Despite the important role of both cyclooxygenase (COX) isoforms (i.e. COX-1 and COX-2) in maintenance of hypersensitivity following peripheral nerve injury, their role in the development of neuropathic pain is not clear. The present study was undertaken to determine the effect of COX inhibitors to address the potential role of COX isozymes in the development of neuropathic pain in rats after c...

This clinical study was carried out to compare the rate of nerve complications after anterior and posterior approaches in forearm both bone fractures in adults. For this purpose, 310 patients with forearm both bone fractures operated during 1997-2002 in Kerman Shahid Bahonar Hospital were studied. From these patients, 121 cases werefemale and 189 cases were male and they were aged from 12 to 67...

Objective(s):Diabetic neuropathy (DN) is a common complication of diabetes that leads to allodynia, impaired nerve conduction, and progressive sensory loss. The aim of this study was to observe the effect of a high-affinity cannabinoid receptors agonist, WIN 55,212-2, on thermal hyperalgesia, nerve conduction velocity and sciatic nerve histopathology in diabetic rats. Materials and Methods: Di...

Recognizing the arterial variations of human upper extremities is of potential clinical practice because this area is involved in arterial handling and invasive medical procedure. During dissection of the left upper limb of a 35-year-old male embalmed cadaver, we saw brachial artery bifurcation in the middle third of proximal portion of the arm. Its medial branch descended along the medial side...

Objective-Effect of local administration of laminin and fibronectin on nerve regeneration was assessed. Design- Experimental study. Animal- Sixty male Wistar rats. Procedures- The animals were divided into four experimental groups (n=15), randomly: In transected group left sciatic nerve was transected and stumps were fixed in adjacent muscle. In treatment group (CHIT/LF) the defect was bridg...

Cell membrane has a critical and vital role in functioning and existence of nerve cells that form central nervous system (CNS) in mammals. Disruption of nerve membrane that normally occurs following an accident injuring spinal cord is known to be the major cause of paralysis. In most occasions, spinal cord injuries are not leading to complete cut in spinal cord fibers but are known to cause cru...

Introduction: Peripheral nerve injury leads to neuropathic pain syndromes and different sensation like allodynia and hyperalgesia. Different animal models of neuropathic pain are used to study the neuropathic pain mechanisms. The present study was performed on two models, (SNI). The purpose of this study was comparing the behavioral responses of yhese two models and the role of saphenous and...