The rodents are an excellent model for understanding the development and plasticity of the visual system. In this study, we explored the feasibility of Mn-enhanced MRI (MEMRI) and diffusion tensor imaging (DTI) at 7 T for in vivo and longitudinal assessments of the retinal and callosal pathways in normal neonatal rodent brains and after early postnatal visual impairments. Along the retinal path...

Background: Neonates born in inappropriately low levels of care outside perinatal centres have high mortality, decline in the neonatal mortality rates after regionalization of perinatal care which emphasised delivery of high risk and preterm infants less than 32 weeks at perinatal centres and establishment of neonatal transport team attending birth when feasible. Aim of the Study: The aim of th...

Vitamin B12 maintains normal folate metabolism which is essential for cell multiplication during pregnancy. No good data are available on what constitutes vitamin B12 deficiency in pregnancy, nevertheless vitamin B12 deficiency is frequently reported in pregnancy due to inadequate dietary intake of vitamin B12 and a physiological decline of maternal vitamin B12 concentrations. This decline can ...

The nuclear and microsomal RNA of three minimal de viation hepatomas and 10-day-old neonatal rat liver were compared by standard DNA-RNA competitive hybridiza tion techniques. nRNA from 5123C hepatoma and 10-day neonatal liver lack sequences present in adult liver nuclear RNA. These missing sequences appear to be identical in part. nRNA from the slowly growing Morris 9618 hepa toma could not be...

ABCA12: adenosine triphosphate binding cassette A12 HI: harlequin ichthyosis NICU: neonatal intensive care unit INTRODUCTION Harlequin ichthyosis (HI) is a rare autosomal recessive congenital ichthyosis associated with mutations in the keratinocyte lipid transporter adenosine triphosphate binding cassette A12 (ABCA12), leading to disruption in lipid and protease transport into lamellar granules...

Congenital chloride diarrhoea (CCD) is a recessively inherited disorder of chloride transport in the distal ileum and colon. Congenital chloride diarrhoea is a common metabolic disorder in Kuwait with an incidence of 1/3200. Clinical findings in 14 children with CCD are reported over a period of 4 years. Maternal polyhydramnios, abdominal distension, watery diarrhoea, and a high faecal chloride...