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Analysis of 108 cases of Neonatal Tetanus by using a scoring system (Tjandra et al., 197 4) revealed that 18 patients belonged to Grade I with a mortality rate of 5.6%; 43 belonged to Grade II wi,th a mortality nate of 58.1%; and 47 belonged to Grade lll wioth 91.5% mortality. The differences of mortality bBtween tthe 3 groups are statistically significant. Mortality rate of 1973 was the lowest...

BACKGROUND The incidence and mortality rates of neonatal tetanus (NNT) remain underreported in Nigeria. The goal of the study was to compare the NNT prevalence and the mortality rates from the existing surveillance system and active surveillance of health facility records in 7 selected health facilities from 2010 to 2014 in Katsina State, Nigeria. METHODS The study is a retrospective record r...

Background and Objectives: HIV infected patients are at risk for vaccine-preventable infections such as tetanus and diphtheria (Td). In these patients, these antibodies tend to decline faster. Due to the limited data, this study assessed the seroprevalence of tetanus and diphtheria antibodies in HIV infected patients in Tehran, Iran. Materials and Methods: This case-control study was carried o...

TO THE EDITOR—Maternal and neonatal tetanus is a significant cause of mortality, estimated to cause 180 000 deaths annually [1]. Since the mid-1970s, tetanus vaccination of pregnant women has been included in the World Health Organization’s (WHO) Expanded Programme on Immunisation (EPI) [2]. Two doses of tetanus toxoid are sufficient to generate an antibody response (immunoglobulin G [IgG] clas...

Conservative management of severe tetanus neonatorum is attended by a very high mortality (Tompkins, 1958; Wright, 1960a; Adams, Holloway, and Thambiran, 1964). Tracheostomy in addition to sedation has not been successful in preventing respiratory failure, which necessitated mechanical ventilation (IPPV) in about 90% of the patients described by Holloway (1967). Although IPPV has been shown to ...

universal vaccination of neonates and children against diphtheria, tetanus and pertussis has had a tremendous impact on the control of these infectious diseases worldwide. immunization by the triple diphtheria, tetanus and whole cell pertussis vaccine (dtwp) has been applied in iran for almost 50 years. periodic assessment of immunogenicity of this vaccine is an important aspect of successful m...

OBJECTIVE To estimate the sensitivity of neonatal tetanus (NNT) surveillance in India. DESIGN A comparison of two sets of data obtained from NNT mortality surveys and routine surveillance system. METHODS NNT mortality surveys were undertaken in 1981, 1989 and 1992 using 30 cluster sampling technique. The data on reported incidence of NNT through routine surveillance system was taken from th...

BACKGROUND Case-control studies previously conducted in Pakistan suggested that topical antimicrobials might provide protection against neonatal tetanus (NNT) when applied to the umbilical cord wound during the first several days of life. The present case-control study, the largest such study yet reported, was undertaken in Punjab Province, Pakistan and afforded further opportunities to evaluat...