Incontinentia pigmenti (IP) is a rare genetic multisystem disorder that may affect many organs including the skin, bone, eyes and the central nervous system. Central nervous system manifestations are seen in 30% of cases with seizures and mental retardation. Seizures occurring as the presenting sign of IP are rarely reported. We report a case of a female newborn with IP who had seizures on day ...

Maternal hypercalcemia suppresses parathyroid activity in the fetus resulting in impaired parathyroid responsiveness to hypocalcemia after birth. Resultant hypocalcemia may be severe and prolonged and rarely may lead to convulsions. Here, we present a newborn infant admitted to the pediatric emergency department at age two weeks with recurrent tonic convulsions due to asymptomatic maternal hype...

OBJECTIVE Early-onset neonatal seizures are a strong predictor of later morbidity and mortality in term infants. Although an association of noninfectious intrapartum fever with neonatal seizures in term infants has been reported, it was based on only a small number of neonates with seizures. We therefore conducted a case control study to investigate this association further. METHODS All term ...

background: x-linked lissencephaly with ambiguous genitalia (xlag) is a recently described genetic disorder, in which patients present with lissencephaly, agenesis of the corpus callosum, refractory epilepsy of neonatal onset, acquired microcephaly, and male genotype with ambiguous genitalia. xlag is responsible for a severe neurological disorder of neonatal onset in boys. a gyration defect con...

The aim of this work is to establish inclusive guidelines on electroencephalography (EEG) applicable all neonatal intensive care units (NICUs). Guidelines ideal EEG monitoring for neonates are available, but there significant barriers their implementation in many centres around the world. These include due limited resources regarding availability equipment and technical interpretive round-the-c...

Seizures are a widespread condition affecting 50~65 million people in the world, and newborns also susceptible to them. EEG is used monitor brain activity of with suspected injuries, followed by qualitative waveform interpretation group clinical experts, where means towards detection seizures include set distinct characteristics waveform. This seizure has been critiqued, particularly due subjec...

Background: Seizure disorder is a common neurologic condition that affects 10% of kids. Febrile seizures are in children between the ages three months and five, with risk factors including genetics, age, gender, fever, type duration seizures, family developmental history, multiple perinatal exposure to anti-retroviral medications, pre-existing abnormalities. Risk include fever-induced substance...

BACKGROUND Ephedrine, unlike phenylephrine, has a dose-related propensity to depress fetal pH during spinal anesthesia during cesarean section. A low arterial umbilical cord pH has a strong association with neonatal mortality and morbidity. The purpose of this retrospective study was to investigate influences of vasopressor change on Apgar scores and adverse neonatal outcomes in cesarean sectio...

Neonatal period is the most vulnerable time for the occurrence of seizures, and neonatal seizures often pose a clinical challenge both for their acute management and frequency of associated long-term co-morbidities. Etiologies of neonatal seizures are known to play a primary role in the anti-epileptic drug responsiveness and the long-term sequelae. Recent studies have suggested that burden of a...

Let g ∈ Q be not −1 or a square. Let Pg denote the set of primes p such that g is a primitive root mod p. Let 1 ≤ a ≤ f, (a, f) = 1. Under the Generalized Riemann Hypothesis (GRH) it can be shown that the set of primes p ∈ Pg with p ≡ a(mod f) has a natural density. In this note this density is explicitly evaluated. This generalizes a classical result of Hooley.