rohrer's ponderal index in newborns (birth weight * 100/height3) has been used as an indicator of fetal growth status, especially to assess asymmetrical intrauterine growth retardation. low ponderal index or disproportionate intrauterine growth retardation has higher neonatal morbidity and there are some specific guidelines in intrauterine growth retarded infants to control some of their p...

UNLABELLED In humanized UDP glucuronosyltransferase-1 (hUGT1) mice that express the entire UGT1 locus, the maternal hepatic UGT1A genes are dramatically induced 12-14 days after conception. Steroid induction of the UGT1A1 gene indicates that xenobiotic sensors, such as the pregnane X receptor (PXR) and constitutive androstane receptor (CAR), may underlie the induction process. In contrast, neon...

Background: Neonatal jaundice is generally a benign condition seen during the postnatal period. The non-invasive methods including transcutaneous bilirubinometry have been developed for assessment of neonatal jaundice, bilirubin TcB) meters noninvasively estimate levels by measuring light transmission through skin neonates this value then to be plotted against chart in order look hyperbilirubin...

OBJECTIVE Breast milk jaundice is a common problem in nursing infants. It has been ascribed to various breast milk substances, but the component or combination of components that is responsible remains unknown. During our study of defects of the bilirubin uridine diphosphate-glucuronosyltransferase gene (UGT1A1) in patients with hereditary unconjugated hyperbilirubinemia (Crigler-Najjar syndrom...

Jaundice is a frequently encountered problem in the neonatal period. It may be associated with hemolytic, enzymatic, metabolic, endocrine disorders or infections. Recently it has been thought to be one of the clinical signs of urinary tract infections (UTIs) in the neonatal period. Although they are concurrently observed, the association between neonatal jaundice and UTI is still unidentified. ...

OBJECTIVE: Neonatal hyperbilirubinemia (N-HB) usually resulted in bilirubin encephalopathy even death in children. The present study was designed to investigate the prevention and intervention initiatives for N-HB. MATERIALS AND METHODS: Case-control method was used to study the effects of early intervention on neonate with hyperbilirubinemia and perinatal factors. A total of 412 N-HB cases (20...

BACKGROUND Hyperbilirubinemia, or jaundice, is a life threatening disorder in newborns. It is a multifactorial disorder with many symptoms. Generally, the physiological jaundice is the most prevalent type however in some regions pathological jaundice is also common. This review article focuses on a brief introduction to jaundice, its types and causes, measuring the bilirubin level, clinical app...

Introduction: Neonatal hyperbilirubinemia is one of the most important factors affecting the auditory system and can cause sensorineural hearing loss. This study investigated the relationship between behavioral hearing thresholds in children with a history of jaundice and the maximum level of bilirubin concentration in the blood.   Materials and Methods: This study was performed on 18 children...