Although nipple-sparing mastectomy (NSM) is being used more frequently, the oncological safety of NSM remains unclear, particularly in young patients (<35 years). The aim of the present study was to compare the rates of local recurrence (LR), disease-free survival (DFS) and overall survival (OS) in young patients with breast cancer who had undergone NSM or conventional mastectomy (CM). The clin...

We present and discuss various formalizations of Modal Logics in Logical Frameworks based on Type Theories. We consider both Hilbertand Natural Deduction-style proof systems for representing both truth (local) and validity (global) consequence relations for various Modal Logics. We introduce several techniques for encoding the structural peculiarities of necessitation rules, in the typed λ-calc...

Tomato spotted wilt virus (TSWV) has one negative sense (L) and two ambisense (M and S) RNAs. The lack of a tractable TSWV reverse genetics system has impeded direct demonstration of gene function and prevented the usual types of pathogen characterization. The TSWV NSm (non-structural) protein has been presumed to be the viral movement protein (MP) based on a few lines of indirect evidence. We ...

BACKGROUND With the evolution of breast reconstruction and oncoplastic techniques, more aesthetic mastectomies are being offered to patients. Nipple-sparing mastectomy (NSM) has been controversial, but an expanding body of published experience has allowed this concept to gain momentum. OBJECTIVES The authors review their experience with NSM. METHODS From 2007 to 2009, 112 consecutive patien...

Nipple-sparing mastectomy (NSM) is challenging in patients with significant ptosis and skin excess. We previously described the first use of a surgical delay (a supraareolar incision with undermining off the breast mound) to facilitate a second-stage pedicled NSM and reconstruction. Here, we present an improvement in our surgical delay technique-a total skin and NSM through Wise incisions. This...

Upper tract urothelial carcinoma (UTUC) is rare and its management presents many challenges. Outside of distal ureterectomy for select cases, management has been primarily radical nephroureterectomy. Endoscopic nephron sparing management (NSM) is recognized to have some role in UTUC treatment; however, it is yet to gain firm footing in the treatment algorithm. In this review, we discuss the ben...

Finding semantic similarity between two natural language entities considered a challenging task in the field of natural language processing. Accuracy of presently existing semantic similarity computational methods is still very far from what humans would perceive. In this paper, we present a new approach of measuring semantic similarity/distance between concepts/words by considering all senses ...

A controversy has existed over the interaction of syntax and semantics in natural language understanding systems. According to theories of integrated parsing, syntactic and semantic processing should take place simultaneously, with the parsing process driven by a single rule base which contains both syntactic and semantic knowledge. This is in sharp contrast to traditional linguistic approaches...