نتایج جستجو برای: natural killer cell activity
تعداد نتایج: 2958670 فیلتر نتایج به سال:
Natural killer (NK) cells, a cytotoxic lymphocyte lineage, are able to kill tumor cells in vitro and in mouse models. However, whether these cells display an anti-tumor activity in cancer patients has not been demonstrated. Here we have addressed this issue in patients with several hematological cancers. We found a population of highly activated CD56(dim)CD16(+) NK cells that have recently degr...
We investigated the relationship between age-related changes in natural resistance and antitumor effects using a spontaneously hypertensive rat (SHR rat) strain which shows a progressive decline of the number of T-cells and their functions as a result of aging. The growth of a weakly antigenic mammary adenocarcinoma SST-2 was significantly suppressed in SHR rats ages 2 and 3 months, whereas in ...
PURPOSE OF THE REVIEW One of the most perplexing features of systemic-onset juvenile rheumatoid arthritis is the association with macrophage activation syndrome, a life-threatening complication caused by excessive activation and proliferation of T cells and macrophages. The main purpose of the review is to summarize current understanding of the relation between macrophage activation syndrome an...
BACKGROUND Patients with gene expression profiling-defined high-risk myeloma in relapse have poor outcomes with current therapies. We tested whether natural killer cells expanded by co-culture with K562 cells transfected with 41BBL and membrane-bound interleukin-15 could kill myeloma cells with a high-risk gene expression profile in vitro and in a unique model which recapitulates human myeloma....
background: infertility is an increasing medical and social problem. in vitro fertilization (ivf) has become a common and accessible treatment for a wide variety of indications that have variable outcomes. natural killer (nk) cells have been identified as relevant immunological factors involved in reproductive success or failure. objective: the aim of this study was to compare the percentage of...
many findings point to the presence of a close relationship between the immune, endocrine and neurologic systems. for example the suppressive effects of β-human chorionic gonadotropin (β-hcg) on il-l production, the potentiative effect of enkephalins on lymphocyte functions and the suppressive effect of leuteinizing hormone (lh) on natural killer (nk) cell activities have been clearly establish...
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