نتایج جستجو برای: national institutes of health stroke scale
تعداد نتایج: 21381360 فیلتر نتایج به سال:
BACKGROUND AND PURPOSE Imaging information has been proposed as a potential surrogate outcome in stroke clinical trials. The purpose of this study was to determine whether an early outcome measure combining clinical and imaging information is better than either alone in predicting 3-month outcome in acute ischemic stroke patients. METHODS Clinical information (National Institutes of Health St...
Background and Purpose: Recently much debate has arisen on the appropriateness of assessing stroke outcomes with stroke impairment scales. Our purpose was to study the relationship between long-term impairments and functional outcomes in terms of disability, handicap, and quality of life. Methods: We studied 87 patients who had a stroke 6 months earlier. Impairments were scored on five stroke s...
BACKGROUND AND PURPOSE Outcome from stroke is highly dependent on baseline conditions. Patients with stroke have a wide range of severities, ages, and etiologies and it has proven difficult to achieve randomization of key variables in clinical trials. We present a new post hoc approach to achieve balance among selected variables. To illustrate the approach, we rebalanced the National Institute ...
The Case A 56-year-old diabetic man presented to the emergency room 45 minutes after right-sided hemiplegia and global aphasia. National Institutes of Health Stroke Scale score, 20; ASPECTS score (Alberta Stroke Program Early CT Score), 9, on computed tomographic (CT) scan; and CT angiography showed terminal ICA T occlusion. Both angio suite and interventionalist are available. No contraindicat...
BACKGROUND AND PURPOSE Prior studies have shown that patients with mild ischemic stroke have substantial disability rates at hospital discharge. We sought to determine disability rates at 90 days among patients not treated with thrombolytic therapy and explore the role of early neurological worsening. METHODS We reviewed a prospective cohort of 136 consecutive patients with mild deficits (Nat...
Background and Purpose—Pneumonia is a major cause of morbidity and mortality after stroke. We aimed to determine key characteristics that would allow prediction of those patients who are at highest risk for poststroke pneumonia. Methods—We studied a series of consecutive patients with acute stroke who were admitted to hospital. Detailed evaluation included the modified National Institutes of He...
Rationale Over half of acute ischemic stroke patients have a low National Institutes of Health Stroke Scale of 0-5 and up to two-thirds may not appear clearly disabled at presentation. The efficacy of intravenous alteplase for the latter group is not known. Aim Potential of rtPA for Ischemic Strokes with Mild Symptoms (PRISMS) was designed to evaluate the safety and efficacy of intravenous alte...
MMP9 variation after thrombolysis is associated with hemorrhagic transformation of lesion and death.
BACKGROUND AND PURPOSE Experimentally, matrix metalloproteinases (MMPs) play a detrimental role related to hemorrhagic transformation and severity of an ischemic brain lesion. Tissue-type plasminogen activator (tPA) enhances such effects. This study aimed to expand clinical evidence in this connection. METHODS We measured MMPs 1, 2, 3, 7, 8, 9, and tissue inhibitors of metalloproteinases 1, 2...
BACKGROUND AND PURPOSE Recently much debate has arisen on the appropriateness of assessing stroke outcomes with stroke impairment scales. Our purpose was to study the relationship between long-term impairments and functional outcomes in terms of disability, handicap, and quality of life. METHODS We studied 87 patients who had a stroke 6 months earlier. Impairments were scored on five stroke s...
The Case A 68-year-old diabetic woman presents to the emergency department 1 hour after right-sided hemiplegia and global aphasia. National Institutes of Health Stroke Scale score is 21; Alberta Stroke Program Early CT score (ASEPCTS) on computed tomographic scan is 8; and computed tomographic angiography shows severe left internal carotid artery stenosis and proximal left M1 middle cerebral ar...
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