Background Eosinophilia is common in patients with atopic dermatitis (AD). Abrocitinib, an oral Janus kinase-1 inhibitor and dupilumab, anti–interleukin-4 receptor-α antibody, are approved for moderate-to-severe AD. Dupilumab has been associated transient eosinophilia. Objectives To assess the effect of abrocitinib dupilumab on eosinophils from phase 3 JADE COMPARE (NCT03720470) EXTEND (NCT0342...

OBJECTIVES To determine the prevalence of eosinophilia in patients with recent-onset arthritis suggestive of rheumatoid arthritis (RA) and to describe their features and outcomes. METHODS We performed an ancillary study of data from a French prospective multicentre cohort study monitoring clinical, laboratory and radiographic data in patients with inflammatory arthritis of 6 weeks to 6 months...

Biologics used in the treatment of rheumatoid arthritis (RA) rarely cause eosinophilia. We herein report a patient with RA being treated with infliximab, adalimumab, and tocilizumab who developed eosinophilia with skin symptoms. Interestingly, the marked eosinophilia and skin symptoms did not reappear after the patient's medication was switched to golimumab. In this case, the presence of biolog...

In 1932, Loffler described a syndrome of self-limiting, transient pulmonary infiltrates associated with peripheral blood eosinophilia and mild pulmonary symptoms. A number of conditions are related to pulmonary eosinophilia or pulmonary infiltration with eosinophilia. Especially, parasitic infestations are often related to pulmonary eosinophilia, but only two cases associated with Clonorchis si...

introduction: septal deviation is the chief cause of chronic nasal obstruction. in order to treat such cases, nasal septoplasty surgery is usually performed based on patient complaints and a surgeon's examination, both of which are subjective. this study aims at using the objective parameters of acoustic rhinometry and rhinomanometry to evaluate the effectiveness of septoplasty surgery.   ...

In BALB/c mice, sensitization with the attachment protein (G) of respiratory syncytial virus (RSV) leads to CD4+ T cell-mediated lung eosinophilia during subsequent challenge with RSV. To determine the host genetic influences on this model of lung eosinophilia, we tested 15 different inbred mouse strains. Eosinophilia developed in all H-2d (BALB/c, DBA/2n, and B10.D2), but not in H-2k (CBA/Ca, ...

Two cases of acute lymphoblastic leukemia process rather than part of it. A mechanism with eosinophilia are described. The degree for the production of the eosinophilia is of eosinophilia was such that at presentadiscussed, and it is suggested, on the basis tion, a provisional diagnosis of eosinoof our findings, that acute eosinophilic philic leukemia was made. Cytogenetic evileukemia may be of...

Allergy and eosinophilia in the gastrointestinal (GI) tract are not equivalent. GI eosinophilia is associated with infections (parasites), nutritional deficiencies, inflammatory processes, neoplasias, and systemic disorders. However, in addition to eosinophilia, other histologic changes usually accompany the increased number of eosinophils in most of these conditions. In contrast, there is a gr...