BACKGROUND Recurrent acute rhinosinusitis is clinically defined as having around four or more episodes per year of active sinus infection with asymptomatic periods in the interim. Clinical practice guidelines recommend a primary evaluation for an acute bacterial infection including a nasal endoscopy. To meet the criteria for acute rhinosinusitis, there must be presence of purulent nasal dischar...

Nasal polyp is one of the common causes of nasal obstruction. The diagnosis is usually made on clinical ground and rarely needs histological examination. However, when a candidate is selected for the surgical option of polyp removal, there is tendency to send all specimens for routine histological examination. The objective of this study was to assess the necessity of routinely performed histol...

OBJECTIVES To investigate the expression and distributional patterns of the inhibitor of apoptosis protein (IAP) family and caspase 3 in nasal polyps and normal nasal mucosa and to evaluate the possible effects of the IAP family and caspase 3 on the development of nasal polyps. DESIGN Prospective study. SETTING Tertiary academic institution. PATIENTS Normal inferior turbinate mucosa was o...

INTRODUCTION Endoscopic sinus surgery is a minimally invasive procedure used to restore normal sinus ventilation and mucociliary function. It is a routine otolaryngology procedure with a success rate of about 90% for symptomatic improvement in patients with refractory chronic rhinosinusitis. Because of the proximity of the paranasal sinuses to the brain and the orbit, it cannot be performed wit...

introduction: there are suspended fungal spores in the air and in the nasal mucosa of adults, especially in areas with a humid climate. several studies have revealed the role of fungi in the pathogenesis of chronic rhinosinusitis (crs) in recent years but it is a topic of controversy, especially in regions with low humidity. the aim of this study was to evaluate the prevalence of fungal species...

PURPOSE OF REVIEW New developments in the nasal and paranasal sinus cancers are reviewed. RECENT FINDINGS In addition to woodworking, several risk factors for nasal and paranasal sinus cancers have been identified, most notably smoking. Progress in the differential diagnosis of small round cell nasal and paranasal sinus cancers allows the precise diagnosis of esthesioneuroblastoma. Despite re...

The effect of surgical procedure on breathing movement and the effect of characteristics of breathing movement on changes in heart rate and blood pressure during actual endoscopic nasal surgery were analyzed using analysis of variance and Bayesian network modeling. As the result, the probabilistic causal relationship between respiratory irregularities, increasing blood pressure and patients’ co...

Endoscopic endonasal approaches are increasingly becoming the state of art in transsphenoidal pituitary surgery. The goal of this study is first to briefly introduce nasal and sphenoidal phases of the approach along with reconstruction phase. Then, the key points of radiologic studies of various parts of the surgery with images and movies are discussed. Difficult cases from 350 surgeries will b...

Methods NP were obtained after endoscopic surgery for chronic rhinosinusitis, and separated into two categories based on eosinophil density. Nasal middle turbinates (MT) were also collected as normal controls from patients who had undergone surgery for pituitary adenomas. To identify cell types expressing isoforms of NOS, double immunostaining was performed using anti-NOS and anti-leukocyte ant...

Back Ground: Sinusitis affects millions of people each year and is a major cause of concern worldwide. Chronic rhino-sinusitis is an inflammation of Nose and Paranasal sinuses and the aetiology of it is multifactorial. Anatomical variations of nose and paranasal sinuses are one of the most important aetiological factor for chronic sinusitis. The approach to patients with chronic rhinosinusitis ...