نتایج جستجو برای: nanosized particle
تعداد نتایج: 177061 فیلتر نتایج به سال:
Purpose: To develop a nanosuspension drug delivery system to enhance the dissolution rate of Silybum marianum seeds extract.
 Methods: Central composite design was used study effect input variables (stabilizer plant extract ratio, antisolvent solvent stirring time) on dependent (mean particle size, polydispersity index (PDI) and zeta potential). The optimized formulation characterized by S...
In this work, the composition, structural and morphological features, particle size of active phase catalyst (MoS2), synthesized in-situ during heavy oil hydroconversion performed in continuous flow reactor on lab-scale pilot unit at T = 450 °C, P 6.0–9.0 MPa, V 1.0 h?1, H2/feed 1000 nL/L, concentration C (Mo) 0.01–0.08%wt have been studied. It has shown that MoS2 formed is represented by nanos...
Slow condensed phase diffusion in organic aerosol particles can impede many chemical and physical processes associated with atmospheric (e.g., gas-particle equilibrium partitioning). The characteristic times these high viscosity are typically modelled using a concentration-dependent diffusivity within purely Fickian framework. In that model, the medium which is taking place treated as being inv...
Polycaprolactone (PCL) is a widely used material in many applications to tackle health problems worldwide. Formed micro- or nanosized PCL particles and fibres benefit from higher surface area volume ratio are valuable those applications, thus there always push achieve smaller diameters. Electrohydrodynamic (EHD) technologies have been at the forefront production of polymeric biomaterials, press...
We are interested in developing hydrophilic particulate systems that are capable of sequestering growth factors, regulating their release and potentiating their biological functions. To this end heparin (HP)-decorated, hyaluronic acid (HA)-based hydrogel particles (HGPs) were synthesized using an inverse emulsion polymerization technique employing divinyl sulfone as the crosslinker. By varying ...
There can be no doubt that nanotechnology will play a major role in our futuretechnology. Computer science offers more opportunities for quantum andnanotechnology systems. Soft Computing techniques such as swarm intelligence, canenable systems with desirable emergent properties. Optimization is an important anddecisive activity in structural designing. The inexpensive re...
Nanosized spherical LiFePO4/C composite was synthesized from nanosized spherical FePO4 ·2H2O, Li2C2O4, aluminum oxide, titanium oxide, oxalic acid, and sucrose by binary sintering process. The phases and morphologies of LiFePO4/C were characterized using SEM, TEM, CV, EIS, EDS, and EDX as well as charging and discharging measurements. The results showed that the as-prepared LiFePO4/C composite ...
The EU Regulation on Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) demands the implementation of alternative methods for analyzing the hazardous effects of chemicals including particulate formulations. In the field of inhalation toxicology, a variety of in vitro models have been developed for such studies. To simulate the in vivo situation, an adequate exposure de...
Although our understanding of RNAi and our knowledge on designing and synthesizing active and safe siRNAs significantly increased during the past decade, targeted delivery remains the major limitation in the development of siRNA therapeutics. On one hand, practical considerations dictate robust chemistry reproducibly providing precise carrier molecules. On the other hand, the multistep delivery...
Recent research has demonstrated that all body fluids assessed contain substantial amounts of vesicles that range in size from 30 to 1000 nm and that are surrounded by phospholipid membranes containing different membrane microdomains such as lipid rafts and caveolae. The most prominent representatives of these so-called extracellular vesicles (EVs) are nanosized exosomes (70-150 nm), which are ...
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