There is an increasing concern about the health hazard posed to workers exposed to inhalation of nanoparticles. Inhaling nanoparticles possess an occupational hazard due to elevated amount emitted to the atmosphere and working environment. Nanoparticles have potential toxic properties: the high particle surface area, number concentration, and surface reactivity. Inhalation, the most common rout...

Nanoparticle toxicology is an emergent field that focuses on establishing the hazards of human exposure to nanoparticles and their potential risk. Accurate assessments of nanoparticles risk involve the investigation of multiple factors such as the nanoparticles parameters, the test system and the cell type. Some nanoparticles may interfere with the toxicity detection assays or the enzymatic act...

Cell model systems in vitro facilitate the high throughput screening of putative toxicity of a variety of nanomaterials, including nanoparticles. However, most of such cell models consisted of non-neural cells. We have developed several central and peripheral neural cell models for the systematic investigation of cytotoxicity of nanomaterials. Our previous finding that the nanoparticles of seve...

An increasing need of nanotechnology in various industries may cause a huge environment dispersion of nanoparticles in coming years. A concern about nanoparticles interaction with flora and fauna is raised due to a growing load of it in the environment. In recent years, several investigators have shown impact of nanoparticles on plant growth and their accumulation in food source. This review ex...

background: the antifungal activity of selenium nanoparticles (se nps) prepared by klebsiella pneumoniae has been reported previously for different fungi. in the present study, freshly prepared se nps produced by k. pneumoniae were purified and characterized by transmission electron microscopy and energy-dispersive x-ray spectroscopy (eds) and its post antifungal effects for two fungi were eval...

Phagocytosis or endocytosis by macrophages is critical to the uptake of fine particles, including nanoparticles, in order to initiate toxic effects in cells. Here, our data enhance the understanding of the process of internalization of silver nanoparticles by macrophages. When macrophages were pre-treated with inhibitors to phagocytosis, caveolin-mediated endocytosis, or clathrin-mediated endoc...

Advances in catalysis rely on the synthesis and characterisation of nanoparticles that have tailored structures and compositions. Although energy-dispersive X-ray (EDX) spectroscopy can be used to study local variations in the compositions of individual supported nanoparticles on the atomic-scale in the scanning transmission electron microscope, electron beam induced damage and contamination ca...

background: in recent years, silver nanoparticles due to their antimicrobial properties, have formed about 56% of nanoparticles global production. since the released nanoparticles ultimately enter water ecosystems, their maximum toxic effects are magnified in aquatic ecosystems. the aim of this study is to show how salinity can decrease the toxic effects of silver nanoparticles on exposed rainb...

backgrounds and objectives: photocatalyst titanium dioxide nanoparticles can oxidize organic and inorganic compounds of microorganisms in aqueous solutions after exposure to uv light. in the present study, the inhibitory effect of titanium dioxide and its photocatalyst type on aspergillus flavus , escherichia coli and staphylococcus aureus is investigated.   materials and methods: toxicogenic s...

Herein we examined the toxicity, penetration properties and ability of Fe2O3·nH2O magnetic nanoparticles extracted from silt of the Borovoye Lake (Krasnoyarsk, Russia) to bind an antibiotic. Experimental studies were carried out using magnetic nanoparticles alone and after antibiotic exposure in tissue samples from nasal mucosa, cartilage and bone (in vitro). Toxicity of particles was studied i...