Interferometric scattering microscopy (iSCAT), as an ultrasensitive fluorescence-free imaging modality, has recently gain enormous attention and been rapidly developing from demonstration of principle to quantitative sensing. Here we report on a theoretical experimental study for iSCAT with samples having structural dimensions that differ by 4-5 orders magnitude. In particular, demonstrate intu...

Metal nanoparticle synthesis is an interesting area in nanotechnology due to their remarkable optical, magnetic, electrical, catalytic and biomedical properties, but there needs to develop clean, non-toxic and environmental friendly methods for the synthesis and assembly of nanoparticles. Biological agents in the form of microbes have emerged up as efficient candidates for nanoparticle synthesi...

Directional bonding interactions in solid-state atomic lattices dictate the unique symmetries of atomic crystals, resulting in a diverse and complex assortment of three-dimensional structures that exhibit a wide variety of material properties. Methods to create analogous nanoparticle superlattices are beginning to be realized, but the concept of anisotropy is still largely underdeveloped in mos...

The precise spatiotemporal delivery of nanoparticles from polymeric capsules is required for applications ranging from medicine to materials science. These capsules derive key performance aspects from their overall shape and dimensions, porosity, and internal microstructure. To this effect, microfluidics provide an exceptional platform for emulsification and subsequent capsule formation. Howeve...

This protocol describes a self-assembly technique to create macroscopic monolayer films composed of ligand-coated nanoparticles. The simple, robust and scalable technique efficiently functionalizes metallic nanoparticles with thiol-ligands in a miscible water/organic solvent mixture allowing for rapid grafting of thiol groups onto the gold nanoparticle surface. The hydrophobic ligands on the na...

In this work, we demonstrate the controlled synthesis of silica nanoparticles as small as 30 nm (±5 nm) and as large as 250 nm (±30 nm) in minutes using surfactant free, microwave-assisted synthetic techniques. Proper choice of solvent, silicic acid precursor, catalyst, and microwave irradiation time were the variables used to control nanoparticle size and, ultimately, overcome the previously r...

Dengue virus (DENV) is the causative agent of dengue fever and dengue hemorrhagic fever. The virus is endemic in over 120 countries, causing over 350 million infections per year. Dengue vaccine development is challenging because of the need to induce simultaneous protection against four antigenically distinct DENV serotypes and evidence that, under some conditions, vaccination can enhance disea...

Nanoparticles can provide significant improvements in the diagnosis and treatment of cancer. How nanoparticle size, shape, and surface chemistry can affect their accumulation, retention, and penetration in tumors remains heavily investigated, because such findings provide guiding principles for engineering optimal nanosystems for tumor targeting. Currently, the experimental focus has been on pa...

The phytochemical and pharmacological studies of leaf, bark and fruit extracts of Samadera indica were carried out on aqueous and methanolic extracts, obtained by soxhlet technique. The qualitative tests showed the presence of carbohydrates, proteins, phenolics, alkaloids, saponins, flavonoids, tannins and resins, whereas quantitative estimations of carbohydrate, protein, phenolics and tannins ...

Experimentally we explore the potential of using pre-defined motion of a receding contact line to control the deposition of nanoparticles from suspension. Stripe-patterned wettability gradients are employed, which consist of alternating hydrophilic and hydrophobic stripes with increasing macroscopic surface energy. Nanoparticle suspensions containing nanorods and nanospheres are deposited onto ...