CONTEXT Diacerein (DCN) has low aqueous solubility (3.197 mg/L) and, consequently, low oral bioavailability (35%-56%). To increase both the solubility and dissolution rate of DCN while maintaining its crystalline nature, high pressure homogenization was used but with only a few homogenization cycles preceded by a simple bottom-up technique. METHODS The nanosuspensions of DCN were prepared usi...

Annealing of amorphous precursor alloys, with compositions (Fe,Co!88M7B4Cu1 ~M5Zr, Nb, Hf!, above their primary crystallization temperature results in the nanocrystallization of the ferromagnetic a8-FeCo phase. This work describes results of the characterization of these alloys, including morphological and chemical stability of the a8-FeCo phase, examination of alloy compositions, and developme...

Group IV quantum dots (QDs) in HfO2 are attractive for non-volatile memories (NVMs) due to complementary metal-oxide semiconductor (CMOS) compatibility. Besides the role of charge storage centers, SiGeSn QDs have advantage a low thermal budget formation, because Sn presence decreases crystallization temperature, while Si ensures higher stability. In this paper, we prepare MOS capacitors based o...

Nanocrystalline LiFe,O, particles embedded in an amorphous matrix were obtained by heat treatments of the nonmagnetic oxide glass 32Li20-8Fe0,-60B203, between 200 and 770'~. The X-ray spectra reveal the formation of the spinel phase of Li-ferrite in the initially amorphous materials only for annealing temperatures higher than 440°C and the hybrid structure becomes more evident with the increase...