Background & objectives: The increased incidence of metabolic diseases (e.g., diabetes and obesity) has seriously affected human health and life safety worldwide. It is of great significance to find effective drugs from natural compounds and exercise to treat metabolic diseases. The aim of this study was to evaluate the effect of berberine chloride with aerobic training on Liver Gene Expressi...

Introduction: Osteoarthritis (OA) is one of the most common joint diseases that is accompanied with cartilage loss and finally leads to joint destruction. The most common joint that is affected in OA is the knee joint. Knee joint OA may lead to significant illness.  Methods: The effect of excessive running load on the development of knee OA was investigated in rats. This study aimed to ev...

Introduction: Neuropathy is the most common neurological complication of diabetes which affects the central nervous systems, especially the brain. The aim of this study was to investigate the effects of resistance training After Transplantation of stem cells on rate of TNF-α and NF-κB in cerebral Cortex of STZ-induced Diabetic Rats. Materials and Methods: : In this experimental study,...

Background: This study aimed to investigate the effect of eight weeks of interval training on gene expression of liver X receptors (LXR) in Wistar male rats. Materials and Methods: In this study, 24 male wistar rats (200-250 g) were randomly used to three groups for this purpose, 24 male Wistar rats were prepared and divided into three groups: control (8 = n), high intensity intermittent exerc...

Background & Objective: Regarding the high prevalence of epileptic seizures, its complications and the necessity to control them, this study was carried out in order to assess the role of progesterone administration in newborn rats on Pentylenetetrazol (PTZ) kindling susceptibility after maturity. Materials & Methods: This experimental study was carried out on 32 newborn Wistar rats. Rats were ...