Synopsis The permeation of chemicals across the nail plate and their consequent effects are discussed in relation to cosmetic toxicity and possible clinical efficacy. The reviewed data are then assessed and placed in context with recent observations on the direct assessment of permeability of the human nail plate. Although marked differences between the diffusional barrier characteristics of na...

The yellow nail syndrome is a scarcely described condition characterized by dystrophic yellowish nails, respiratory disturbances and lymphedema; while the pincer nail deformity is characterized by thickening and excessive transverse curvature of the nail plate. The objective of this case study is to report a 76-year-old Japanese descent woman with yellow nail syndrome and pincer nails, intestin...

Although several manifestations of skin involvement in cases of amyotrophic lateral sclerosis (ALS) have been reported, the pincer nail deformity has not been previously reported in a patient with ALS. The pincer nail deformity is characterized by distortion of the shape of the nail with transverse over curvature and may be associated with systemic diseases and certain medications. We herein de...

BACKGROUND An estimated 3700 individuals are seen annually in US emergency departments for nail gun-related injuries. Approximately 45 cases have been reported in the literature concerning nail gun injuries penetrating the cranium. These cases pose a challenge for the neurosurgeon because of the uniqueness of each case, the dynamics of high pressure nail gun injuries, and the surgical planning ...

Nails can act as a protective, defensive and beauty cover of the phalanges. The dermatologic disorders as well as the systemic diseases and trauma can produce change in the nails. Normal variations of nails are important to recognize and distinguish from nail diseases. There is not enough information about the prevalence of nail disorders in children. In this study, we have determined the preva...

Ingrown toenail, or onychocryptosis, most commonly affects the great toenail. Many anatomic and behavioral factors are thought to contribute to ingrown toenails, such as improper trimming, repetitive or inadvertent trauma, genetic predisposition, hyperhidrosis, and poor foot hygiene. Conservative treatment approaches include soaking the foot in warm, soapy water; placing cotton wisps or dental ...

OBJECTIVE To report an unusual reaction associated with weekly administration of paclitaxel. CASE SUMMARIES Onycholysis was seen in four women with recurrent ovarian cancer being treated with low-dose, weekly paclitaxel. Two of the patients had previously received higher doses of paclitaxel on an every-three-week schedule without similar reactions. Onycholysis developed between weeks 10-13 of...

OBJECTIVES The aim of this 7-year follow-up study was to determine respiratory changes in dental technicians. MATERIAL AND METHODS In our region, in the year 2005, 36 dental technicians were evaluated with a cross-sectional study on respiratory occupational diseases, and in 2012 we evaluated them again. Inclusion of information on respiratory symptoms and demographic features questionnaires w...

A sixty-one year old white female was referred to the Dermatology Department to treat an ingrown nail in the inner corner of the left hallux. Examination of the entire nail unit showed the presence of xanthonychia in the outer corner besides thickening and increase in the transverse curvature of the nail plate. Dermoscopy and nuclear magnetic resonance of the free edge of the nail plate detecte...

OBJECTIVE To evaluate the clinical characteristics and treatment outcomes of patients undergoing surgical nail avulsion. DESIGN Retrospective study. SETTING Two dermatology centres in Hong Kong. PATIENTS A total of 32 patients with nail diseases who underwent 33 nail avulsion procedures were reviewed from case records. MAIN OUTCOME MEASURES Age, gender, co-morbidities, disease duration,...