Overgaard, Kristian, Tue Lindstrøm, Thorsten Ingemann-Hansen, and Torben Clausen. Membrane leakage and increased content of Na -K pumps and Ca2 in human muscle after a 100-km run. J Appl Physiol 92: 1891–1898, 2002. First published January 4, 2002; 10.1152/japplphysiol.00669. 2001.—During prolonged exercise, changes in the ionic milieu in and surrounding the muscle fibers may lead to fatigue or...

This study investigated the recovery of renal proximal tubule cellular (RPTC) functions following oxidant-induced sublethal injury. tert-Butylhydroperoxide (TBHP) treatment resulted in 24% cell death and loss 4 h following the exposure. The remaining sublethally injured RPTC proliferated, and monolayer DNA content returned to control values on day 4 following TBHP exposure. Basal oxygen consump...

To investigate whether Na(+) uptake by zebrafish is dependent on NH4(+) excretion, a scanning ion-selective electrode technique was applied to measure Na(+) and NH4(+) gradients at the yolk-sac surface of zebrafish larvae. Low-Na(+) acclimation induced an inward Na(+) gradient (uptake), and a combination of low Na(+) and high NH4(+) induced a larger inward Na(+) gradient. When measuring the ion...

The colon is a major site for fermentation and water absorption in the ostrich. Water absorption along the colon was evaluated and its relationship to osmolality, Na+ concentration, short chain fatty acid (SCFA) concentration and carbohydrate content of digesta analysed. Mean water content decreased from 5.30 +/- 0.99 to 2.51 +/- 0.13 mf/g dry mass in the first 5 m of the colon. Correspondingly...

That Ca is decreased and K increased in cancerous tissues as compared to the corresponding normal ones, has hitherto been reported by many workers.110> DeLong et al.5 1 reported that the diminution in Ca content is peculiar to cancer and responsible for the decreased mutual adhesiveness of cancer cells. They also reported that the increased K content is merely one of the expressions of cellular...

A hemolytic disorder characterized by altered RBC cation composition (increases Na, decreases K), reduced monovalent cation content (decreased Na + K/liter RBC), and decreased levels of 2,3-diphosphoglycerate (2,3-DPG) is described. The etiology of these RBC abnormalities was not elucidated following extensive laboratory evaluation, although two important physiologic principles were manifested ...

Rheumatoid arthritis (RA) is a chronic inflammatory disease whose cause remains obscure. Blood from 15 RA patients and controls was taken and their ghosts separated. The ghosts were analysed for cholesterol content, Na+/K+ ATPase activity and eicosapentaenoic acid. The cholesterol content in the ghosts of RA patients was significantly lower as compared with the set of controls. There was a majo...

Two types of leaching tests were performed on the bottom ash from municipal solid waste incinerators. A short-term batch test specified by the America Nuclear Society (ANS) and long-term column tests with acetic acid (pH 5.2) as leaching solution were used to evaluate copper leachability. The Cu leaching after the 5-d ANS test is about 1% of the original Cu content of 5300 mg/kg. Upon addition ...

The effects of irrigation water salinity on growth, chlorophyll contents, proline and nutrients accumulation and K/Na ratio in three walnut cultivars was investigated. Three irrigation water salinity levels with electrical conductivities of 1,5, 3, and 5.0 dS/m and tap water as a control treatment were used in a randomized design with four replications. Irrigation practices were realized by con...

Muscular K uptake depends on skeletal muscle Na-K-ATPase concentration and activity. Reduced K uptake is observed in vitro in K-depleted rats. We evaluated skeletal muscle K clearance capacity in vivo in rats K depleted for 14 days. [(3)H]ouabain binding, alpha(1) and alpha(2) Na-K-ATPase isoform abundance, and K, Na, and Mg content were measured in skeletal muscles. Skeletal muscle K, Na, and ...