Background. Desnutrin is an enzyme that catalyzes the first step of cytoplasmic triacylglycerol lipolysis from white adipose tissue and several other tissues, which are disrupted by the obesity and metabolic syndrome. Objectives. The aim of this study was to compare the effect of high-intensity interval training and continuous training on the desnutrin gene expression in the subcutaneous adipo...

Background: There is a growing concern on the impact of the presence of extended-spectrum β-lactamase (ESBL) producing Escherichia coli isolated from animals on public health. OBJECTIVES: The aim of this study was to investigate the presence of three classes of ESBL genes in E. coli isolates from sheep and broilers at a slaughter in Urmia region, Iran. METHODS: A total of 111 E. coli isolates w...

Metabolic syndrome and its pathological sequel, type 2 diabetes are considered as important global health problems. Metformin is the most common drug prescribed for patients with this disorder. Consequently, understanding the genetic pathways involved in pharmacokinetics and pharmacodynamics of this drug can have a considerable effect on the personalized treatment of type 2 diabetes. In this st...

N-terminal acetylation is a highly abundant protein modification catalyzed by N-terminal acetyltransferases (NATs) NatA-NatG. The Saccharomyces cerevisiae protein Arl3 depends on interaction with Sys1 for its localization to the Golgi and this targeting strictly requires NatC-mediated N-terminal acetylation of Arl3. We utilized the Arl3 acetylation-dependent localization phenotype as a model sy...

This study aimed to investigate whether a specific genotype of the MTNR1A gene influences social dominance and reproductive performance in rams. Thirty-one rams were genotyped for Rsal Mnll polymorphism gene: CC (n=19), CT (n=5), TT (n=7), GG (n=20), GA (n=6), or AA respectively. Maintenance (standing still, lying down, drinking, feeding, walking, stereotyping) behavior (agonistic antagonistic ...

background apo-lipoprotein e (apoe) and carnitine palmitoyltransferase1-a (cpt1-a) genes are well known to be involved in the pathophysiology of psychiatric disorders such as schizophrenia but regarding their cpg island methylation status data is sparse. objectives the aims of the current study were to highlight the effect of the promoter “hypermethylation” in the development of scz. patients a...

background: there is a growing concern on the impact of the presence of extended-spectrum β-lactamase (esbl) producing escherichia coli isolated from animals on public health. objectives: the aim of this study was to investigate the presence of three classes of esbl genes in e. coli isolates from sheep and broilers at a slaughter in urmia region, iran. methods: a total of 111 e. coli isolates w...

This study was designed to identify genetically resistant animals to gastrointestinal nematode (GIN) infections using microsatellite polymorphisms of Ovar-DRB1 gene in Iranian Ghezel sheep breed lambs. In the present study 120 male Ghezel lambs were at 4 to 6 months of age randomly selected from six different sheep flocks in East Azerbaijan province (n=20 per flock). These lambs were naturally ...