An efficient and green protocol for the synthesis of pyrazoles derivatives by one-pot reaction of different 1,3-dicarbonyl compounds with hydrazines/hydrazides has been developed using nano-sulfated zirconia, nano-structured ZnO, nano-g-alumina and nano-ZSM-5 zeolites, as the catalyst. The optical properties of the nano-structured catalysts and organic molecules were studied. The advantages of ...

Brønsted acid promoted nucleophilation of propargylic alcohols during the Meyer-Schuster rearrangement (M-S) has been introduced. A novel concept of reverse polarization of the M-S intermediate allenyl cation has been realized by employing a cis-enoate assisted strategy. This idea is well demonstrated by the metal free synthesis of complex, highly functionalized cyclic as well as acyclic α-aryl...

Diazocoupling reaction of curcumin with different diazonium salts of p-toluidine, 2-aminopyridine, and 4-aminoantipyrine in pyridine yielded the arylhydrazones 2a-c. Arylhydrazone of p-toluidine reacted with urea, thiourea, and guanidine nitrate to produce 5,6-dihydropyrimidines. Further reaction of 2a with 2,3-diaminopyrdine in sodium ethoxide solution yielded 1H-pyrido[2,3-b][1,4]diazepine de...

This work examines theoretically the problem of migration borane groups between nitrogen atoms pyrazolyl rings. We have studied as a model BH2 derivatives pyrazol-1-yl to determine effects substituents on pyrazole ring; also 1-(9-borabicyclo[3.3.1]nonan-9-yl)-1H-pyrazoles compare calculated barriers with experimental ones well steric effects, i.e. how buttressing effect increases rate. The inte...

Abstract The one‐bond nucleophilic reactivities of seven cyclic α‐diazo carbonyl compounds in dichloromethane were determined by analyzing the kinetics their reactions with benzhydrylium ions (one‐bond reference electrophiles) at 20 °C according to Mayr‐Patz equation. Though not calibrated for pericyclic reactions, identified nucleophilicities also reflect relative 1,3‐dipolar cycloadditions di...