1-[N, O-Bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazine (KN-62) and N-[1-[N-methyl-p-(5 isoquinolinesulfonyl)benzyl]-2-(4 phenylpiperazine)ethyl]-5-isoquinolinesulfonamide (KN-04) potently inhibit the human lymphocyte P2Z receptor, an ATP-gated cation channel [Br J Pharmacol 120:1483-1490 (1997)]. Although the molecular identity of the lymphocyte P2Z receptor has not been est...

Inclusive neutrino and antineutrino processes and the problem of the spin of proton * Abstract The inclusive NC and CC neutrino(antineutrino)-nucleus scattering for the case of a nucleus with isotopic spin equal to zero is considered. It is shown that the measurement of the neutrino-antineutrino asymmetry at relatively small energies could allow to obtain model-independent information about the...

The addition of O-linked N-acetylglucosamine (GlcNAc) to the major nuclear pore complex glycoprotein p62 was examined. Expression of the rat p62 cDNA in transfected monkey cells was detected using a rat p62-specific antipeptide antiserum and two previously described nuclear pore-specific monoclonal antibodies which require O-linked GlcNAc for binding. Although the p62 cDNA was predicted to enco...

The vocal training is useful for beginners to learn how to correctly sing, and for professional singers to tune their voice and expand their frequency range. In the paper, we propose a study on vocal training by analyzing voice pitch on android platform. Vocal training requires a vocal coach who is always besides you to correct your mistakes. However, beginner who wants to learn singing for fun...

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Of 416 samples taken from veterinary staff (n = 30), dogs (n = 356) and various environmental sites (n = 30) at the Small Animal Hospital, Faculty of Veterinary Medicine, Chiang Mai University, Thailand, 13 samples contained methicillin-resistant Staphylococcus aureus (MRSA), of which 1 (SCCmec type II) came from veterinarian, 9 (SCCmec types I, III, IVa, V and untypeable) from dogs, and 3 (SCC...

According to Harter (1985a), global self-worth (GSW) can be predicted from the relationship between perceptions of competence and importance ratings. In this study, we employed Harter's (1985b) Importance Rating Scale (IRS) and Self-Perception Profile for Children (SPPC) to examine importance ratings, discrepancy scores, and domain-specific perceptions of competence as predictors of GSW. Childr...

CD spectroscopy on the double-stranded strictly alternating dinucleotide polymer (dT-dG)n . (dC-dA)n partially modified by N-acetoxy-N-acetyl-2-aminofluorene suggests a left-handed conformation in concentrated NaCl solutions. Modification of the (dT-dG)n . (dC-dA)n polymer with acetylaminofluorene is required to promote formation of the left-handed helix since high salt concentrations and sever...