Though lipomas are very common tumors occurring in the head and neck region, there are very few case reports of submucosal lipomas of the upper aerodigestive tract. A case of myxoid lipoma of the supraglottic region is reported.

Although cases of lipoma are common, angiomyxolipoma is a rather rare variant composed three basic components: myxoid stroma, mature adipose tissue and many blood vessels. We reported the case 71-year-old man who was found to have mass at knee level, subsequently surgically removed, which be compatible with angiomyxolipoma.