نتایج جستجو برای: myocardial stunning
تعداد نتایج: 158506 فیلتر نتایج به سال:
Cardiac diseases are characterized by a host of changes to the cellular processes that affect contractility of the heart. One emerging experimental approach to the study of cardiac disease, including the ischemia/reperfusion injury known as stunning, is to identify proteins that have been specifically altered or modified in the diseased state. Minimally, the identification of modified proteins ...
BACKGROUND Myocardial stunning has been associated with a greater than twofold increase in intracellular free [Mg2+] from 0.6 to 1.5 mM. The effect of this increase in free [Mg2+] on the function of the sarcoplasmic reticulum (SR) Ca2+ pump was assessed in SR isolated from Langendorff perfused, isovolumic rabbit hearts after 15 minutes of global ischemia. METHODS AND RESULTS Our results indic...
OBJECTIVES The goal of this study was to investigate the effect of three different doses of acetylsalicylic acid (aspirin) (ASA) on the late phase of ischemic preconditioning (PC) against myocardial stunning. BACKGROUND Although recent evidence indicates that the late phase of ischemic PC is mediated by cyclooxygenase-2 (COX-2), the effect of nonsteroidal anti-inflammatory drugs (NSAIDs) that...
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