Early diagnosis and localisation of myocardial perfusion defects is an important step in the treatment of coronary artery disease. The assessment of myocardial perfusion requires accurate quantification of the transmural extent of possible defects, which involves a complete multi-slice coverage of the ventricle at a given phase of the cardiac cycle. To this end, a number of rapid imaging sequen...

UNLABELLED Compared with conventional coronary angiography, spiral multidetector CT (MDCT) angiography has delivered promising accuracy in the detection and validation of coronary lesions. Myocardial perfusion imaging (MPI) using SPECT is an established method for noninvasively assessing the functional significance of coronary stenoses and delivers valuable information for risk stratification. ...

First-pass contrast-enhanced myocardial perfusion MRI in rodents has so far not been possible due to the temporal and spatial resolution requirements. We developed a new first-pass perfusion MR method for rodent imaging on a clinical 3.0-T scanner (Philips Healthcare, Best, The Netherlands) that employed 10-fold k-space and time domain undersampling with constrained image reconstruction, using ...

Movement of the patient during myocardial perfusion SPECT leads to some artifacts that make the interpretation difficult. In this study, myocardial perfusion imaging protocol was performed on a cardiac phantom and SPECT was performed by simulating patient movements. A lesion model with dimensions of 1.2 × 2 × 2 cm was created on the inferoseptal wall of the cardiac phantom. Imaging was done in ...

background current teaching suggests increased perfusion in free transverse rectus abdominis myocutaneous (tram) flaps over pedicled tram flaps, broadening indications for its use in high risk patients. this study compared perfusion analysis of free muscle-sparing versus pedicle tram flaps in vivo in the peri-operative and late post-operative periods. methods the spy-elite system using indocyan...

Methods Three hundred forty-one self-referred asymptomatic subjects were enrolled in this study. CMRA image quality and factors affecting image quality were evaluated using a 1.5-T scanner with a 32-channel cardiac coil. Coronary artery stenosis, regional wall motion abnormalities, myocardial perfusion abnormalities, and delayed myocardial enhancement were analyzed. The occurrence of new chest ...

UNLABELLED PET allows for quantitative, regional myocardial perfusion imaging. The short half-lives of the perfusion tracers currently in use limit their clinical applicability. Here, the biodistribution and imaging quality of a new 18F-labeled myocardial perfusion agent (18F-BMS-747158-02) in an animal model are described. METHODS The biodistribution of 18F-BMS-747158-02 was determined at 10...

Introduction: Myocardial perfusion imaging (MPI) is an important imaging modality in managing patients with cardiovascular disease. MPI has a significant role in diagnosis and management of cardiovascular disease; however it is subjected to different artifacts. Combining pharmacologic stress with submaximal exercise reduces side effects, improves image quality, and enhances the...

This review considers the changing nature of surgical risk assessment and the definition of risk; discusses the pathophysiology of perioperative myocardial infarction in relation to tests of coronary flow reserve; surveys the extensive literature on preoperative myocardial perfusion imaging (MPI) and outlines key trends; presents practical points on image interpretation; addresses the needs of ...