BACKGROUND Severe-early childhood caries (S-ECC) is one of the most common infectious diseases in children and is prevalent in lower socio-economic populations. American Indian children suffer from the highest levels of S-ECC in the United States. Members of the mutans streptococci, Streptococcus mutans, in particular, are key etiologic agents in the development of caries. Children typically ac...

This study evaluated the effect of some plaque and salivary factors on caries progression in situ. The salivary secretion rate, buffering capacity and mutans streptococci counts from 13 volunteers were determined. For three distinct periods of time, 4, 7 and 10 days, each of them wore a palatal appliance containing 4 bovine enamel blocks. They used a non-fluoridated dentifrice during the experi...

Controlling the growth of cariogenic microorganisms such as oral streptococci is an adjunct therapy for caries-active individuals to prevent and treat caries. Here we investigated the antimicrobial activity of the synthetic amphipathic α- helical antimicrobial peptide GH12 (GLLWHLLHHLLH-NH2) against oral streptococci in vitro. Circular dichroism studies showed that GH12 takes on an α-helical co...

background: one of the causative factors in development of dental caries is microorganisms. two species of mutans streptococci including streptococcus mutans and streptococcus sobrinus are associated with dental caries in human beings. the aim of this study was to investigate the frequency of s. mutans and s. sobrinus in saliva of children with different caries activity and ability to form biof...

Streptococcus mutans, the primary etiologic agent of dental caries, possesses a series of virulence factors associated with its cariogenicity. Alternatives to traditional antimicrobial treatment, agents selectively inhibiting the virulence factors without necessarily suppressing the resident oral species, are promising. The anticariogenic properties of tea have been suggested in experimental an...

background:   to find out if there is an association between levels of salivary mutans streptococci (ms)   materials and methods:   t -test were used to find differences between groups. p   results:   p   p   p   conclusion:   present study showed a strong association between maternal and child salivary   ms levels indicating that mother’s ms count could be an important risk indicator for ecc d...

The present study compared IgA specificity against oral streptococci in colostrum and saliva samples. Sixty-two mother-and-child pairs were included; samples of colostrum (C) and saliva (MS) were collected from the mothers and saliva samples were collected from babies (BS). The specificity of IgA against Streptococcus mutans and S. mitis were analyzed by western blot. Only 30% of babies' sample...

We previously found that tonsillar application of antigen induces a strong antibody response to Streptococcus sobrinus in saliva and blood plasma. Rabbits immunized against S. sobrinus by tonsillar application were highly resistant to experimental dental caries triggered by oral inoculation of living S. sobrinus organisms with sucrose. In the present study, we examined the reaction of S. sobrin...

statement of the problem: dental caries is the most common disease of childhood. using probiotics has recently been introduced to reduce the incidence of dental caries.it consists of live microbial food supplements that beneficially affect the host, and hence are considered an alternative way to eradicate the infections. purpose: the aim of this study is to evaluate the effect of consumption of...

The aim of this study is to determine the sensitivity of polyphenol green tea on mutans streptococci. Tea is a traditional drink that is beneficial to health. One of its benefits is its capability to prevent dental caries because it has active substance polyphenol.An extract of green tea non-fermented tea leaves of Camellia sinensis and its chromatographically isolated polyphenol compound was e...