INTRODUCTION The aim of this study is to determine the anti-mutagenic effects of Vitamin E among nurses of oncology and non-oncology hospitals exposed to chemotherapy drugs. Several studies have demonstrated that nurses occupationally exposes to cytostatic drugs. MATERIAL AND METHODS A total of 138 female nurses from oncology and non-oncology hospitals participated in the study. All urine sam...

Adriamycin and menogarol are anthracyclines which cause more than 100% increase in life span of mice bearing P388 leukemia and B16 melanoma. Unlike Adriamycin, menogarol does not bind strongly to DNA, and it minimally inhibits DNA and RNA synthesis at lethal doses. Adriamycin is a clinically active drug, and menogarol is undergoing preclinical toxicology at National Cancer Institute. In view of...

Quantum dots as nanocrystals of semiconductor materials are synthesized with different methods. The green synthesis fluorescent quantum using natural stabilizing agents has attracted much attention. This research aims to study the ability Teucrium polium L. extract synthesize silver (AgQDs). AgQDs was proved UV–Visible spectrophotometer, Fourier Transform Infrared spectroscopy (FTIR), X-Ray Dif...

Mixture design has been used to identify possible interactions between mutagens in a mixture. In this paper the use of mixture design in multidimensional isobolographic studies is introduced. Mutagenicity of individual nitro-polycyclic aromatic hydrocarbons (PAH) was evaluated is an organic extract of diesel exhaust particles (DEPs). The particles were extracted with dichloromethane (DCM). Afte...

Dimethylnitrosamine (DMN) was mutagenic in the Salmonella plate incorporation assay (Ames test) at a level of 10 mumol/plate (3.7 mM) in the presence of hamster liver S-9. Mutagenicity of DMN at this level was not observed when the S-9 was derived from mouse or rat liver, although the mouse liver and hamster liver S-9 had similar DMN demethylase activities. Both mouse and rat liver S-9 inhibite...

The objective of this study is to evaluate the stability activated sludge (AS) in treatment kraft pulp mill effluent exposed black liquor shock, as well effect its exposure on morphology Daphnia magna and DNA damage through mutagenicity genotoxicity response Salmonella typhimurium. To end, we applied doses 2-, 4-, 10-, 30-mL liquor/L influent—shock 1 (S1), shock 2 (S2), 3 (S3), 4 (S4), respecti...

Polycyclic aromatic hydrocarbons are compounds with 2 or more benzene rings, and 16 of them have been classified as priority pollutants. Among them, pyrene has found in higher concentrations than recommended, posing a threat to the ecosystem. Many bacterial strains identified degraders. Most belong Gram-positive such Mycobacterium sp. Rhodococcus These were enriched isolated from several sites ...