PURPOSE Expression of cellular adhesion molecules is altered in bullous keratopathy. The hypothesis that epithelial alterations in bullous keratopathy compromise the surface of the cornea and its glycocalyx was tested. METHODS Studies were performed on eight cases each of pseudophakic bullous keratopathy and healthy corneas. The number of epithelial cell layers was determined with a stereolog...

A high incidence of band keratopathy was observed in a rabbit colony being utilized in uveitis experiments. Unrelated to the uveitis, the animals had developed, in addition to the corneal lesions, deposits of calcium in the kidneys, arterial tree, trachea, and smooth muscle of the intestine suggestive of hypercalcemia due to an accidental hypervitaminosis D. The clinical and histopathologic cha...

PURPOSE To determine the type and prevalence of epithelial abnormalities in the intermediate postoperative period after penetrating keratoplasty and to define the donor and recipient variables that influence the status of the graft epithelium. DESIGN Prospective cohort study. METHODS We prospectively followed the clinical course of 80 patients after penetrating keratoplasty. We monitored th...