RATIONALE Obstructive sleep apnea syndrome is due to upper airway obstruction and is associated with increased morbidity. Although continuous positive airway pressure efficaciously treats obstructive apneas and hypopneas, treatment is impeded by low adherence rates. OBJECTIVES To assess the efficacy on obstructive sleep apnea of a minimally intrusive method for delivering warm and humidified ...

The prevalence of obstructive sleep apnea syndrome in patients up to the age of 60 is known to be two times higher in men then in women. Hormonal changes during menopause might underlie changes in this relationship in the elderly. This study was designed to detect differences in the type and frequency of sleep-disordered breathing between women and men over the age of 65 years, having the same ...

Current treatment options are successful in 40% to 60% of children with persistent obstructive sleep apnea after adenotonsillectomy. Residual obstruction assessments are largely subjective and do not clearly define multilevel obstruction. We endeavor to use computational fluid dynamics to perform virtual surgery and assess airflow changes in patients with Down syndrome and persistent obstructiv...

INTRODUCTION Patients with obstructive sleep apnea syndrome usually present with changes in upper airway morphology and/or body fat distribution, which may occur throughout life and increase the severity of obstructive sleep apnea syndrome with age. OBJECTIVE To correlate cephalometric and anthropometric measures with obstructive sleep apnea syndrome severity in different age groups. METHOD...

Obstructive sleep apnea occurs frequently in patients with drug-resistant hypertension. The factors accounting for this observation, however, are unclear. Both conditions demonstrate clinical features suggestive of extracellular fluid volume overload. The aims of this study were to examine whether the spontaneous overnight fluid shift from the legs to the upper body is associated with obstructi...

background and objective: obstructive sleep apnea syndrome (osas) is a prevalent disease in adults. limited evidence regarding the effect of severity of sleep apnea and depression on heart rate variability (hrv) indices exists. hence, we decided to focus on the association between hrv and severity of osas based on depression score. materials and methods: a total of 193 patients with confirmed o...

Obstructive sleep apnea represents a significant public health concern. Afferent vagal activation is implicated in increased apnea susceptibility by reducing upper airway muscle tone via activation of serotonin receptors in the nodose ganglia. Previous investigations demonstrated that systemically administered cannabinoids can be used therapeutically to decrease the apnea/hypopnea index in rats...

BACKGROUND Lipomas are common benign tumors, but they rarely occur in the retropharyngeal space and even more rarely occur in children. CASE REPORT We report the case of an 11-year-old girl with a 5-year history of progressively worsening nasal obstruction, snoring, and excessive daytime sleepiness. Physical examination revealed a child with a body mass index of 16.9 kg/m2; otolaryngologic ex...

BACKGROUND Obstructive sleep apnea occurs as a result of increased collapsibility of the upper airway. Overnight fluid displacement from the legs to the neck causes pharyngeal narrowing and increased apnea severity. Sodium intake is associated with apnea severity. We hypothesized that interventions that decrease bodily fluid content might reduce the severity of sleep apnea. METHODS/DESIGN Thi...

OBJECTIVE The prevalence of complex sleep apnea syndrome (CompSAS) among Asian patients with obstructive sleep apnea syndrome (OSAS) has not yet been reported. Distinguishing CompSAS from pure OSAS is difficult using only diagnostic polysomnography (PSG). We examined the prevalence of CompSAS in Japanese patients with OSAS and the possibility to distinguish CompSAS from pure OSAS by analyzing t...