background and objective: hyperalgesia is one of the marked clinical signs of patients with diabetes mellitus that affects their lifestyle. this study was conducted to assess the anti-nociceptive effect of chronic administration of curcumin in streptozotocin (stz)-diabetic rats using formalin, hot tail immersion, and paw pressure tests. materials and methods: this study was conducted on 40 male...

We have demonstrated that fifth-order stimulated Raman spectra of the intermolecular modes in CS 2 are dominated by cascading third-order processes. Previous studies have successfully discriminated against a sequential cascading process, but did not account for parallel third-order cascades. All of our measured spectra were successfully simulated considering only cascades built directly from ou...

Abstract Typically, monitoring quality characteristics of very personalized products is a difficult task due to the lack experimental data. This typical case processes where production volume continues shrink growing complexity and customization products, thus requiring low-volume productions. paper presents novel approach statistically monitor defects-per-unit (DPU) assembled based on use defe...

multistage stochastic programming is a key technology for making decisions over time in an uncertain environment. one of the promising areas in which this technology is implementable, is medium term planning of electricity production and trading where decision makers are typically faced with uncertain parameters (such as future demands and market prices) that can be described by stochastic proc...

Receptor-mediated apoptosis proceeds via two pathways: one requiring only a cascade of initiator and effector caspases (type I behavior) and the second requiring an initiator-effector caspase cascade and mitochondrial outer membrane permeabilization (type II behavior). Here, we investigate factors controlling type I versus II phenotypes by performing Lyapunov exponent analysis of an ODE-based m...

The Integral Input to State Stability (iISS) property is studied is the context of nonlinear time-invariant systems in cascade. Some sufficient conditions for the preservation of the iISS property under a cascade interconnection are presented. Those are first given as growth restrictions on the supply functions of the storage function associated to each subsystem, and then are expressed as solu...

One of the existing problems of multi-attribute process monitoring is the occurrence of high number of false alarms (Type I error). Another problem is an increase in the probability of not detecting defects when the process is monitored by a set of independent uni-attribute control charts. In this paper, we address both of these problems and consider monitoring correlated multi-attributes proce...

Abstract The influence of impurity doping on GaAs-based two-well resonant-phonon terahertz quantum cascade lasers is investigated theoretically, and efficient schemes are discussed. By using the rate equation model, impacts dopant amount, position, distribution performance a high-performance device simulated focusing single module. calculated optical gain found to have peak over range sheet den...

There are several novel anticoagulants in development that target factor Xa(FXa)-the pivotal point of the coagulation cascade. One promising agent is rivaroxaban (a highly selective, oral, direct FXa inhibitor), which is in advanced clinical development for the prevention and treatment of thromboembolic disorders. Oral rivaroxaban may be given in fixed once-daily doses, with the potential for n...