Confocal laser endomicroscopy (CLE) is a new endoscopic imaging technology that allows real-time, high-resolution observation of tomographic images mucosal cells and subcellular levels in vivo, detecting microscopic structural changes morphology, its vivo immediate pathological diagnostic capability can avoid delays diagnosis reduce the pain caused by repeated biopsies. CLE known as “optical bi...

The present study was designed with the aim to determine oral health status of hospitalized patients, to assess oral symptoms and to ascertain percentage of oral lesions/symptoms noticed and treated by the attending physician. The study was conducted on 300 patients admitted in a medical college. All patients were interviewed for presence of oral symptoms using a structured questionnaire. Syste...

OBJECTIVE The aim of this study was to determine the prevalence of oral mucosal lesions in institutionalized elderly people in Mashhad, northeast of Iran. BACKGROUND This study was conducted to assess the prevalence of oral lesions in the institutionalized elderly. METHODS In this survey, we studied all of the nursing homes in Mashhad; a total of five encompassing 237 residents. The subject...

immunohistochemical demonstration of tumor-associated markers may be valuable as an adjunct to conventional histology for determination of malignancy development in oral mucosal diseases. accordingly, the present study determined the distribution of some important tumor markers such as heat shock proteins (hsp), fibroblast growth factors (fgf) and transferrin receptors (tf-r) in 22 samples of p...

Effects of TA-2711 on gastric mucosal lesions induced by various necrotizing agents and several defensive factors of gastric mucosa were investigated in rats. Oral administration of TA-2711 at 12.5 to 200 mg/kg prevented the formation of gastric mucosal lesions induced by 99.5% ethanol, 0.6 N HCl, 0.2 N NaOH and boiling water with ED50 values of 24, 58, 16 and 101 mg/kg, respectively. Oral TA-2...

background and aims. reactive hyperplasias (rhs) are common oral mucosal lesions caused by irritation of the mu-cosa. the aim of this study was to evaluate the frequencies of various types of oral rhs in a university clinic. materials and methods. oral rh cases, undergone biopsy in a four-year period, were studied retrospectively. data including age and gender as well as the location and clinic...

BACKGROUND Rosiglitazone, an insulin sensitizing agent, has been recently implicated in the control of inflammatory processes and modulation of expression of various cytokines such as tumor necrosis factor (TNF-α). However, its mechanistic effect of gastric mucosal integrity remains to be elucidated. METHODS The present study was designed to determine effect of rosiglitazone on gastric mucosa...

BACKGROUND A variety of oral mucosal lesions and conditions are associated with the habit of smoking and chewing tobacco, and many of these carry a potential risk for the development of cancer. There have been no studies that report the prevalence of habits and associated oral changes in the population in Dharwad region, of Karnataka, south India. MATERIALS AND METHODS A hospital-based, cross...

Immunohistochemical demonstration of tumor-associated markers may be valuable as an adjunct to conventional histology for determination of malignancy development in oral mucosal diseases. Accordingly, the present study determined the distribution of some important tumor markers such as heat shock proteins (HSP), fibroblast growth factors (FGF) and transferrin receptors (TF-R) in 22 samples ...

granular cell tumors are rare neoplasms of uncertain histogenesis but with a typical histologic appearance composed of cells with characteristic granular cytoplasm. these tumors occur most often in adults as an asymptomatic solitary papule or nodule. multiple granular cell tumors are rare, especially in children and teenagers. we represent a case of multiple granular cell tumors in a 19-year-ol...