Abstract: Objectives: The intention of present study is to formulate and optimize the famotidine mucoadhesive tablets y using Central Composite Design. Materials Methods: concentrations Cordia dichotoma fruit mucilage powder (X1) Polyvinyl pyrrolidone (X2) were demonstrated as independent variables. Whereas, dependent variables selected such an in vitro Mucoadhesion Time percentage Drug Release...

In the present investigation an attempt has been made to design efficacious and prolonged release mucoadhesive tablet of salbutamol sulphate using various polymers to avoid the first pass metabolism to reduce dossing frequency and to improve patient compliance. Mucoadhesive buccal tablet of salbutamol sulphate were fabricated with objective of avoiding first pass metabolism and to improve its b...

Food and probiotic bacteria, in particular lactic acid bacteria, are ingested in large amounts by humans and are part of the transient microbiota which is increasingly considered to be able to impact the resident microbiota and thus possibly the host health. The lactic acid bacterium Lactococcus lactis is extensively used in starter cultures to produce dairy fermented food. Also because of a ge...