BACKGROUND Antiretroviral therapy (ART) extends life for patients with human immunodeficiency virus (HIV) infection. However, HIV treatment is lifelong, and adherence presents a special challenge. Suboptimal adherence to ART may lead to disease progression and virologic failure. Earlier studies with combination ART demonstrated that as much as 90%-95% adherence was needed to prevent disease pro...

BACKGROUND Research has demonstrated that variation in availability and utilization of health care resources exist on a range of scales, from regions of the United States, hospital referral regions, ZIP codes, and census tracts. Limited research using spatial analyses has found that variation in medication adherence exists across census tracts. Using spatial analysis, researchers may be able to...

One of the best mobility metrics is the Link Duration (LD) that presents how long two nodes are connected. OLSR is one of the most popular ad-hoc routing protocols. Multipoint Relays (MPR) is used by OLSR for controlled flooding. In this paper, we introduce a new approach to select a MPR in OLSR by using the simplest modification and no additional packet header. This approach introduces the ide...

The performance of three serological tests manufactured in Belarus for the diagnosis of syphilis, i.e. a microprecipitation reaction (MPR) and two enzyme-linked immunosorbent assays (ELISAs) were compared with internationally recognized assays, namely the rapid plasma reagin test and the Treponema pallidum passive particle agglutination assay (TPPA). Sera from 392 consecutive patients attending...

The MPR technology in the OLSR routing protocol is described, it is pointed out that there are some limitations when the default heuristic algorithm in this protocol is used to find the minimum MPR. In this paper, an improved algorithm based on node localization is proposed combined with node localization technology. Node localization information is used in this algorithm, the blindness is redu...

Constrained skyline queries retrieve all points that optimize some user’s preferences subject to orthogonal range constraints, but at significant computational cost. This paper is the first to propose caching to improve constrained skyline query response time. Because arbitrary range constraints are unlikely to match a cached query exactly, our proposed method identifies and exploits similar ca...

Relying on a simple flag-assisted mechanism, a multigroup priority queueing (MGPQ) medium access control (MAC) protocol is proposed for the wireless networks with multipacket reception (MPR). The proposed MGPQ scheme is capable of overcoming two major performance bottlenecks inherent in the existing MPR MAC protocols. First, the proposed solution can automatically produce the list of active use...

Background Coronary artery disease (CAD) is a source of significant mortality and morbidity in diabetes mellitus (DM). Abnormal myocardial perfusion reserve (MPR) has been shown to predict worse outcome in patients with diabetes, but limited data is available using CMR. The correlation of MPR derived from Cardiac Magnetic resonance imaging (CMR) with plaque burden on cardiac computed tomography...

The 67-amino acid cytoplasmic tail of the cation-dependent mannose 6-phosphate receptor (CD-MPR) contains a signal(s) that prevents the receptor from entering lysosomes where it would be degraded. To identify the key residues required for proper endosomal sorting, we analyzed the intracellular distribution of mutant forms of the receptor by Percoll density gradients. A receptor with a Trp19 -->...