نتایج جستجو برای: mpe of pk parameters

تعداد نتایج: 21180535  

Journal: :Epilepsy research 2013
Gaoxiang Ouyang Jing Li Xianzeng Liu Xiaoli Li

Understanding the transition of brain activities towards an absence seizure, called pre-epileptic seizure, is a challenge. In this study, multiscale permutation entropy (MPE) is proposed to describe dynamical characteristics of electroencephalograph (EEG) recordings on different absence seizure states. The classification ability of the MPE measures using linear discriminant analysis is evaluate...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس - دانشکده مهندسی مکانیک 1392

تولید شبکه فرایندی بسیار پرهزینه و مشکل، بخصوص برای مسائل با تغییر شکل زیاد و هندسه های پیچیده، می باشد؛ از این رو، در سال های اخیر توجه ویژه ای از طرف محققین مختلف به توسعه ی روش های بدون شبکه معطوف شده است. روش sph که یک روش ذره ای و کاملاً لاگرانژی بوده و بدون استفاده از شبکه به حل میدان محاسباتی می پردازد نیز یکی از این روش ها می باشد. قابلیت های ذاتی این روش در شبیه سازی مسائل با تغییر شکل ...

2009
Erik McDermott Shinji Watanabe Atsushi Nakamura

Using the central observation that margin-based weighted classification error (modeled using Minimum Phone Error (MPE)) corresponds to the derivative with respect to the margin term of margin-based hinge loss (modeled using Maximum Mutual Information (MMI)), this article subsumes and extends margin-based MPE and MMI within a broader framework in which the objective function is an integral of MP...

1998
Willem L. van Meurs Michael L. Good

Pharmacokinetic-pharmacodynamic (PK-PD) models play an important role in educational simulations. The parameters of PK-PD models described in the scientific literature are obtained from studies in which the drug concentrations and the drug-effect data are measured simultaneously. Simultaneous PK-PD studies cannot be expected to incorporate all possible combinations of drugs and patient physiolo...

2012
Markus Nußbaum-Thom Zoltán Tüske Georg Heigold Ralf Schlüter Hermann Ney

We recently discovered novel discriminative training criteria following a principled approach. In this approach training criteria are developed from error bounds on the global error for pattern classification tasks that depend on non-trivial loss functions. Automatic speech recognition (ASR) is a prominent example for such a task depending on the non-trivial Levenshtein loss. In this context, t...

2013
Meixu Song Qingqing Zhang Jielin Pan Yonghong Yan

Introducing pronunciation models into decoding has proven beneficial for LVCSR. As Minimum Phone Error (MPE) training has almost become a standard scheme for acoustic modeling, a discriminative pronunciation modeling method is investigated under the framework of MPE training. In order to bring the pronunciation models into MPE training, the auxiliary function of MPE training is rewritten at wor...

2007
Jiang Lei

[Abstract] In this paper, the transport efficiency of Multi Protocol Encapsulation (MPE), Unidirectional Lightweight Encapsulation (ULE) and Generic Stream Encapsulation (GSE) for typical IP packet sizes is compared. Moreover, the aggregated efficiency when applying packet-level forward error correction (PL-FEC) with MPE, ULE and GSE is also analyzed. MPE-FEC is the mechanism used by DVB-H wher...

Journal: : 2022

Bu çalışmada püskürtmeli kurutucuda mikroenkapsüle edilmiş propolis ekstraktı (MPE) %0.05, %0.1 ve %0.2 oranlarında hazır muz aromalı puding formülasyonlarına katılmıştır. Bulgulara göre MPE düzeyinin artışına bağlı olarak depolama süresince örneklerinde nem içeriğinde azalma görülmüştür (p

Journal: :Seizure 2012
Na He Fu-Li Min Yi-Wu Shi Jing Guo Xiao-Rong Liu Bing-Mei Li Jin-Hua Zhou Yang-Mei Ou Jian-Xiang Liao Wei-Ping Liao

PURPOSE Oxcarbazepine (OXC) is a promising alternative for patients who cannot tolerate carbamazepine. Recently, however, it has been reported that OXC-induced cutaneous adverse drug reactions (cADRs) are prevalent and may lead to drug discontinuation. Additionally, these reactions are thought to be associated with HLA-B*1502. This study aims to investigate the incidence, features and risk fact...

Alexis Díaz-García, Caridad Rodríguez Torres, Gilmara Pimentel González, Hermis Rodríguez Sánchez, Iraida Sánchez Monzón, Irania Guevara Orellanes, Juan C. Rodríguez Aurrecochea, Maikel Hernández Gómez, Maria Regla Rodríguez Capote, Tais Basaco Bernabeu,

Introduction: Rhopalurus junceus scorpion venom has shown potential for anticancer treatment. However, there are no scientific evidence about venom pharmacokinetic (PK) and biodistribution (BD) in tumor-bearing mice. Methods: 131I-labeled venom was administrated by intravenous (IV) and oral (PO) routes at the single dose of 12.5 mg/kg. Mice were sacrificed and blood samples, major organs, and t...

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