Furosemide is a weakly acidic diuretic indicated for treatment of edema and hypertension. It has very poor solubility but high permeability through stomach and upper gastrointestinal tract (GIT). Due to its limited solubility it has poor and variable oral bioavailibility of 10-90%. The aim of this study was to enhance the oral bioavailibilty of furosemide by preparation of nanosuspensions. The ...

analyzing the nonlinear vibration of beams is one of the important issues in structural engineering. according to this, an impressive analytical method which is called modified iteration perturbation method (mipm) is used to obtain the behavior and frequency of a cantilever beam with geometric nonlinear. this new method is combined by the mickens and iteration methods. moreover, this method don...