Gu and Zheng (1993) established a Bartlett adjustment for the partial likelihood ratio test in the Cox proportional hazards regression model. It is known that the same method of adjustment cannot be used to improve the accuracy of the test statistic derived by Rao’s score method. In this paper, the method of Cordeiro and Ferrari (1991) is used to derive a Bartlett type correction for the score ...

INTRODUCTION AND AIMS the precise role of parenteral nutrition in the management of oncologic patients with intestinal occlusion is not well defined yet. We aimed to identify the effects of parenteral nutrition in these patients regarding prognosis. MATERIAL AND METHODS 55 patients with intestinal occlusion and peritoneal carcinomatosis were included. Parenteral nutrition aimed at 20-35 kcal/...

Background and Objectives: To evaluate the predictive factor for and patterns of distant metastasis in patients with rectal adenocarcinoma receiving total mesorectal excision (TME). Methods: We enrolled 217 consecutive patients who had histologically confirmed rectal adenocarcinoma and underwent surgery at Taipei Medical University- Wanfang Hospital between January 2000 and December 2014. TME w...

IL-1a, an important regulator of immune and inflammation responses, has been implicated in cancer development and prognosis. An insertion (Ins)/deletion (Del) polymorphism (IL-1a rs3783553) in the 3' UTR of IL-1a may disrupt a binding site for miRNA-122 and may affect its transcription level. Thus, this polymorphism may cause interindividual variation in immune and inflammation responses and th...

Patients with small cell lung carcinoma (SCLC) present neuroendocrine (NE) properties and chromogranin A (CGA), synaptophysin (Syn), and neural cell adhesion molecule 1 (NCAM1) are known as NE diagnostic markers, while the predictive value of the NE differentiation in SCLC remains uncertain. The aim of this retrospective study was to evaluate the prognostic significance of NE markers in tissue ...

Abstract Background To investigate the effect of nicergoline on rate complete corneal ulcer reepithelialization (CCUR) in diabetic rats with keratopathy. Methods Forty-eight streptozotocin-induced were randomly divided into two groups. The experimental group ( n = 24) received (10 mg.kg − 1 .day ), while control (n a placebo. A epithelial defect was induced using diamond burr, and area compared...

Previous studies have reported that alcohol dehydrogenase (ADH) isoenzymes possess diagnostic value in gastric cancer (GC). However, the prognostic value of ADH isoenzymes in GC remains unclear. The aim of the present study was to identify the prognostic value of ADH genes in patients with GC. The prognostic value of ADH genes was investigated in patients with GC using the Kaplan-Meier plotter ...

 We consider the problem of model selection in vector autoregressive model with Normal innovation. Tests such as Vuong's and Cox's tests are provided for order and model selection, i.e. for selecting the order and a suitable subset of regressors, in vector autoregressive model. We propose a test as a modified log-likelihood ratio test for selecting subsets of regressors. The Europe oil prices, ...

PURPOSE The aim of this work was to analyze the results of palliative HDR brachytherapy in patients with advanced esophageal cancer. METHODS AND MATERIALS Ninety-one patients with unresectable, advanced esophageal cancer were treated palliatively by HDR brachytherapy. All patients received a total dose of 22.5 Gy in three fractions per week. Remissions of dysphagia and other clinical and radi...