Articulatory exploration enables the infant to discover abilities of the vocal tract and learn relationships between movements and percepts. However, neither direct measurements nor transcription methods have access to tongue configurations in pre-linguistic infant vocalizations. A statistical articulatory–acoustic model integrating the non-linear growth of the human vocal tract was used to des...

background: for xenograft models of triple-negative breast cancer (tnbc) to be valuable in development of molecularly-targeted drugs, careful characterization is essential to their validation. the present study aimed to validate the tnbc xenograft model with a specific focus on angiogenesis. methods : twelve tnbc xenograft tumors and 12 human breast cancer tumors (htnbc) were included in this s...

a new structure learning approach for bayesian networks (bns) based on asexual reproduction optimization (aro) is proposed in this letter. aro can be essentially considered as an evolutionary based algorithm that mathematically models the budding mechanism of asexual reproduction. in aro, a parent produces a bud through a reproduction operator; thereafter the parent and its bud compete to survi...

In this paper, we propose and analyze a mathematical model describing the effect of awareness programs by public media on the prevalence of Typhoid fever. A threshold quantity $R_{0}$, similar to the basic reproduction number is derived. We investigate the biologically meaningful equilibrium points and their local stability analysis. The global stability analysis has been performed with respect...

Human performance can seriously degrade under demanding tasks. To improve performance, agents can reason about the current state of the human, and give the most appropriate and effective support. To enable this, the agent needs a model of a specific person’s functional state and performance, which should be valid, as the agent might otherwise give inappropriate advice and even worsen performanc...

Early estimates of the transmission potential of emerging and re-emerging infections are increasingly used to inform public health authorities on the level of risk posed by outbreaks. Existing methods to estimate the reproduction number generally assume exponential growth in case incidence in the first few disease generations, before susceptible depletion sets in. In reality, outbreaks can disp...

In many problems from different disciplines such as engineering, physics, medicine, and biology, a series of experimental data is used in order to generate a model that can describe a system with minimum noise. The procedure for building a model provides a description of the behavior of the system under study and can be used to give a prediction for the future. Herein a novel hierarchical bi-le...