Cerebral superoxide anion generation during bicuculline-induced seizures was measured in newborn pigs. Using two closed cranial windows inserted over the parietal cortices, superoxide dismutase (SOD)-inhibitable nitroblue tetrazolium (NBT) reduction was determined during 20 min of seizure activity induced by bicuculline, 5 mg/kg i.v. A modest increase in SOD-inhibitable NBT reduction was observ...

The purpose of this study is to evaluate ultrasonic suture welding of monofilament suture in an animal model of rotator cuff repair with biomechanical and histologic analyses. We randomly assigned 46 shoulders in 23 rabbits to 1 of 3 treatment groups: sham-operated (n = 15), knotted (n = 15), and welded (n = 16). Supraspinatus defects were surgically created and acutely repaired with suture anc...

abstract background: bruising is an unpleasant result of subcutaneous injection of enoxaparin, which causes physical discomfort, limitation of injection site, patient’s refusal of treatment, and distrust in nurses’ ability. the application of techniques which reduce patients’ fear, anxiety, and physical damage is one of the tasks of nurses. this clinical trial investigated the effect of duratio...

Rationale and ObjectivesTo evaluate whether quantitative diffusion-weighted MR imaging (DWI) with multi-b values can be used as a tool to predict the aggressiveness by using histological feature of extrathyroidal extension (ETE) in papillary thyroid carcinoma (PTC).Materials Methods238 patients were pathologically confirmed PTCs underwent preoperative value DWI (300, 500, 800 s/mm2) between Jan...

BACKGROUND/AIMS To evaluate the effect of hepatic steatosis on the apparent diffusion coefficient (ADC) of hepatic fibrosis in patients with HCV genotype 4-related chronic hepatitis. MATERIALS AND METHODS Overall, 268 chronic hepatitis C patients (164 males and 104 females) underwent liver biopsy for fibrosis assessment by the METAVIR score and grading for hepatic steatosis. They were classif...

OBJECTIVE This study evaluates the feasibility, reliability and reproducibility of electrocardiogram (ECG)-gated intravascular ultrasound (IVUS) image acquisition during automated transducer withdrawal and automated three-dimensional (3D) boundary detection for assessing on-line the result of coronary stenting. BACKGROUND Systolic-diastolic image artifacts frequently limit the clinical applic...

BACKGROUND AND PURPOSE Selective regional sensitivity and delayed damage in cerebral ischemia provide opportunities for directed and late therapy for stroke. Our aim was to characterize the spatial and temporal profile of ischemia-induced changes in cerebral perfusion and tissue status, with the use of noninvasive MRI techniques, to gain more insight in region-specific vulnerability and delayed...

Imidazoline (I(1))-evoked hypotension is linked to enhanced phosphorylated extracellular signal-regulated kinase (pERK)1/2 production in the rostral ventrolateral medulla (RVLM). Recent cell culture findings suggest that nischarin is a candidate for the I(1) receptor. In the present study, nischarin antisense oligodeoxynucleotide (ODN) (AS1 or AS2), designed according to nischarin cDNA sequence...