The evidence is reviewed that a single genetic system, the major histocompatibility locus in man, HL-A, determines most of the antigens measured by presently available leukocyte isoantisera, and also controls reactivity in one-way mixed leucocyte culture tests. Studies in 12 families are presented to support this conclusion. Some interesting exceptions to the general typing-MLC tests correlatio...

We studied the effects of hyperthermia (up to 43°)on the cytolytic activity (''Cr release assay) and differentia tion of primary and secondary cytolytic T-lymphocytes (CTL) in vitro. Mixed-leukocyte cultures were established from splenic leukocytes of C57BL/6 mice and DBA/2 stimulator lymphocytes, and the CTL formed on Day 4 (primary) or on Day 21, 3 days after restimulation of the cultures wi...

BACKGROUND Successful transfusion of platelet refractory patients is a challenge. Many potential donors are needed to sustain human leukocyte antigen matched-platelet transfusion programs because of the different types of antigens and the constant needs of these patients. For a highly mixed population such as the Brazilian population, the pool size required to provide adequate platelet support ...

INTRODUCTION Polymerase chain reaction (PCR) method has improved the diagnosis rates for patients with community-acquired pneumonia (CAP). We aimed to evaluate the bacterial and viral etiology of hospitalized CAP cases and compare clinical and laboratory findings of patients with pure bacterial and bacterial and viral (mixed) infections. METHODOLOGY A total of 55 patients hospitalized with CA...

BACKGROUND: It is known that during normal pregnancy and after immunotherapy blocking antibodies are developed, these antibodies inhibit mixed lymphocyte reaction and are also anti-mitogenic in nature. Mixed lymphocyte reaction blocking antibodies are specific to the husband's lymphocytes. In the present study an attempt has been made to characterize the mixed lymphocyte reaction blocking antib...

By CHEV KIDS0N C ATALASE is an enzyme found in most body tissues which has the capacity to release molecular oxygen from hydrogen peroxide ( H202 ) . It is concerned with peroxidation of substrates such as alcohol, phenol, formate and formaldehyde.1 Catalase in blood has aroused considerable interest, the enzyme content being higher than that in other tissues except liver.2 Most studies have co...

introduction: studies have shown that insufficient recovery between sessions causes immune suppression. the aim of this study was to investigate the effect of repeated bouts resistance and endurance exercise on blood leukocytes, lymphocytes, neutrophils, monocytes count and plasma cortisol levels in athlete girls. materials and methods: 9 athlete girls (ages, 20-25 years), participated in the s...