Effective fragment potential (EFP) molecular modeling approaches have been applied for the first time to the rational design of molecularly imprinted polymers for the group recognition of selected polychlorinated biphenyls (PCBs). EFP calculations were benchmarked using the S22 compound test set and returned energies within 1 kcal mol(-1) of the reported gold standard CCSD(T) approach, but with...

HYPOTHESIS Minimally invasive parathyroidectomy (MIP) for primary hyperparathyroidism (HPT) has equal cure and recurrence rates as standard cervical exploration. Changes in the management of primary HPT have occurred since introducing MIP including localization, anesthesia, intraoperative parathyroid hormone monitoring, and indications for parathyroidectomy. DESIGN Cohort analysis of 1361 con...

Previously we showed that cytokine-induced neutrophil chemoattractant (CINC), but not macrophage inflammatory protein-2 (MIP-2), is detected in plasma after intratracheal challenge with LPS or the particular chemokines. To further understand the differences between CINC and MIP-2 flux from the lung, we attempted to detect the two chemokines in isolated erythrocytes and leukocytes in rats after ...

Water homeostasis and the structural integrity of the vertebrate lens is partially mediated by AQP0 channels. Emerging evidence indicates that external pH may be involved in channel gating. Here we show that a tetraploid teleost, the Atlantic salmon, retains 4 aqp0 genes (aqp0a1, -0a2, -0b1, and -0b2), which are highly, but not exclusively, expressed in the lens. Functional characterization rev...

This study was aimed to investigate the roles of serum macrophage inflammatory protein-3α (MIP-3α) and cystatin A in nasopharyngeal carcinoma (NPC) prognosis.The serum levels of MIP-3α and cystatin A in 140 primary NPC patients without distant metastasis were detected by enzyme-linked immunosorbent assay before and after treatment. The results were compared with those in 100 healthy controls. T...

The purpose of this paper is to examine the current status of malaria in pregnancy (MiP) in India and review current control measures, programmes and interventions that work, and to suggest areas that need to be addressed. MiP can have serious health consequences for both the mother and infant, and thus presents a major public health challenge. Roll Back Malaria (RBM), a supporting agency of th...

Reliable characterization of the pore structure is essentially important for transport-related durability studies cementitious materials. Mercury intrusion porosimetry has been commonly used measurement while ink-bottle effect significantly affects trustworthiness size features Pressurization-depressurization cycling mercury (PDC-MIP) an alternative approach previously reported with purpose to ...

To understand the basis of pathogenesis by Legionella longbeachae serogroup 1, the importance of the Mip protein in this species was examined. Amino-terminal analysis of the purified, cloned L. longbeachae serogroup 1 ATCC 33462 Mip protein confirmed that the cloned gene protein was expressed and processed in an Escherichia coli background. DNA sequence analysis of plasmid pIMVS27, containing t...

objective: among the members of legionellaceae, legionella pneumophila is involved in 95% of cases of severe pneumonia. isolation of the causative agent from bronchoalveolar lavage (bal) fluid specimen is a delicate process and also time-consuming. moreover, it has been shown that some legionella strains may be viable but cannot be cultured. the aim of this study was comparison of culture and p...