At the present stage, acne is considered as a multifactorial dermatosis, in formation of which significant role played by genetically determined hyperandrogenism and impaired secretion sebaceous glands, well changes skin microbiome. It known that risk occurrence severity disease are significantly influenced various environmental components, commonly called exposure factors. This article provide...

Skin microbiota is involved in acne pathology. C. acnes, S epidermidis, and Malassezia genus are known to play a role the dysbiosis of acne, but few studies explored entire microbiota. We performed pharmaco-clinical study compare microorganism populations between non-lesioned areas (NLA) subjects, without papules pustules, healthy subjects. showed significant differences diversity, richness, eq...

Abstract Acne is common and results in significant burden patients with acne frequently receive prolonged oral antibiotics leading to antimicrobial resistance. Oral spironolactone prescribed for acne, although there a paucity of evidence on its effectiveness. The aim this pragmatic parallel, double-blind, superiority trial was assess the effectiveness systemic adult women. Participants were ide...

background although, melasma is most prevalent among asian young women, and also darkly pigmented individuals are particularly prone to developing post inflammatory hyperpigmentation, to the best of our knowledge, there are rare or no studies about the association of melasma and post inflammatory hyperpigmentation. results we found out that 24.1% of patients without melasma had post-acne pigmen...

topical retinoids are considered as the first line therapy in the treatment of acne vulgaris, but they are associated with cutaneous irritation. in this study, isotretinoin-loaded solid lipid nanoparticles(it-sln) were prepared to treat the mild to moderate acne. also using it-sln would minimize it adverse effects in comparison to commercial product, isotrex®. this study was conducted to prepar...

Objective: To compare the efficacy of nadifloxacin alone and with benzoyl peroxide in the treatment of mild to moderate facial acne vulgaris. Patients and Methods: This double-blind, randomized study was conducted in a total of 93 acne patients, with at least 10 inflammatory lesions, but no more than 3 nodules or cysts on the face. All patients were instructed to apply nadifloxacin 1% cream twi...

This study in Jordan described the pattern of acne in 166 untreated acne patients aged 13-42 years attending dermatology clinics and assessed patients' perceptions of factors that have an effect on their acne condition. Family history of acne was positive in 69.3% of acne patients. Emotional stress, hot weather and sweating were believed to be aggravating factors by acne patients of both sexes,...

BACKGROUND AND OBJECTIVES Fractional treatment with a dual wavelength 1,064 and 532 nm picosecond-domain laser, delivering a 10 × 10 array of highly focused beamlets via a holographic optic, was investigated for the treatment of acne scars. STUDY Twenty-seven of 31 subjects completed the study, 19 were treated using 1,064 nm and 8 were treated at 532 nm, all having four-monthly treatments. Bl...

The Gulf Journal of Dermatology and Venereology INTRODUCTION The term acne is derived from Greek word “acme” meaning “prime of life”. Though considered as a benign disorder, it can have profound psychological impact on the patients, especially with those having disfiguring scars, which can persist for life.1 It is a chronic inflammatory disorder of pilosebaceous unit resulting from increased se...

Transgender and gender diverse persons face specific skin health disparities. Little is known about the severity, distribution, impact of acne in setting gender-affirming hormone therapy. Our aim to examine severity distribution transgender its association with quality life depression symptoms. Participants were surveyed tertiary academic endocrinology dermatology clinics a public safety-net mu...