Ethylenediamine-soluble glycoproteins were extracted from isolated Microsporum gypseum hyphal walls during sporulation and from spore coats before and after germination. This study was carried out to identify a sporulation-specific cell wall protein that possibly served as a substrate for the alkaline protease which initiated the macroconidial germination of this fungus. Analyses revealed that ...

CONTEXT Due to increase in the number of patients with impaired immunity, incidence of dermatophytoses has increased considerably. Antidermatophytic agents with anti-inflammatory and protease-inhibiting activities will help in restricting inflammatory response associated with dermatophytoses. AIMS The present study aims to evaluate antidermatophytic and protease-inhibiting activities of zerum...

Dermatophytes are filamentous fungi that affect both human and animal skin, hair, nails. There is a public health issue with it. In order to ascertain the effects of methanolic extracts Buccholzia coriacea on isolates sensitivity level common antifungal drugs, this study was developed explore prevalence from clinical cases in horses. Samples were initially cultivated Sabouraud dextrose agar, th...

two series (a and b) of n- substituted heteroaromatic compounds related to clotrimazole were synthesized. imidazole ring of the clotrimazole was replaced by 2-methylimidazole in series a, and by 2-methyl-4-nitroimidazole in series b. o-cholortrityl moiety of clotrimazole was also replaced by trityl, mono or dimethoxy trityl. chemical structures of all the new compounds were confirmed by spec-tr...

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