This paper presents a review, analysis and comparison of numerical methods implementing the curvature motion and the affine curvature motion for 2D images, shapes, and curves. These curvature scale spaces allow, in principle, to compute an accurate multiscale curvature in digital images. The fastest and most invariant of them can be used in a complete image processing chain. This numerical chai...

The incorporation of the microscope in clinical endodontics has had profound effects on the way endodontics is done and has changed the field fundamentally. This article outlines the key prerequisites for the use of the microscope in nonsurgical endodontic procedures, discusses which procedures benefit from using the microscope, and addresses the issue of cost versus patient benefit.

This project report covers the development of a computational 3D microscope, NoScope. Using tomographic and light field algorithms, we present a method to reconstruct 3D volumes of microscopic samples taken with a lensless sensor. Business and intellectual property strategies for commercializing NoScope are detailed in the first three sections. The remaining sections highlight the project’s tec...

In microscopy, regions of interest are usually much smaller than the whole slide area. Various microscopy related medical applications are liable to benefit greatly from microscope auto positioning in previously defined regions of interest. In this paper we present a method for image-based auto positioning on a microscope slide. The method is based on localization of a microscopic query image u...

Dutch envoy to the court of France, mentions the Dutch spectacle-maker Hans Jansen and his son Zacharias as inventors of the first compound microscope in 1595. Their microscope had two lenses combined in a tube in which the magnification was varied by altering the distance between the lenses. However, the Jansens are not known to have published any observations through their microscope; instead...

Microarray technology is a rapidly advancing area, which is gaining popularity in many biological disciplines from drug target identification to predictive toxicology. Over the past few years, there has been a dramatic increase in the number of methods and techniques available for carrying out this form of gene expression analysis. The techniques and associated peripherals, such as slide types,...

The Imaging Computational Microscope (ICM) is a suite of computational tools for automated analysis of functional imaging data that runs under the cross-platform MATLAB environment (The Mathworks, Inc.). ICM uses a semi-supervised framework, in which at every stage of analysis computers handle the routine work, which is then refined by user intervention. The main functionality of ICM is built u...