Introduction: In Senegal, there is very little data on prolactinomas despite their negative impact couples fertility. Patients and methods: This was a multicentre, retrospective, descriptive, analytical study conducted from 1 January 2008 to 31 December 2022 in the neurosurgery departments of Fann Principal hospitals endocrinology department Abass Ndao Hospital. Results: We included 89 patients...

Dilated Cardiomyopathy in a Patient With Acromegaly: Echocardiographic Development After Treatment Acromegaly is a disease characterized by chronic growth hormone (GH) hypersecretion.1 Cardiovascular alterations such as hypertension (HT), left ventricular hypertrophy, and ischemic heart disease are common in this condition and represent the main cause of death.2 Nevertheless, dilated cardiomyop...

1. Attending Physician in the Neuroradiology Department, University of São Paulo Medical School (FMRP-USP), Radiologist at Cedirp, Ribeirão Preto, SP, Brazil. E-mail: [email protected]. The sellar and parasellar regions constitute an anatomically complex area comprising various important neurovascular structures within a small space. The sellar region includes the sella turcica and the pi...

INTRODUCTION Clinical nonfunctional pituitary microadenomas, also known as incidentalomas are accidental observations made due to the application of high resolution imaging techniques as computed tomography or magnetic resonance. There are no standards regarding the follow-up of these tumors and taking into account their increased frequency among general population (during the last years they w...

BACKGROUNDANDPURPOSE: The pituitary gland is located outside of the blood-brain barrier. Dynamic T1 weighted contrast enhanced sequence is considered to be the gold standard to evaluate this region. However, it does not allow assessment of intrinsic permeability properties of the gland. Our aim was to demonstrate the utility of radial volumetric interpolated brain examination with the golden-an...

Resistance to thyroid hormone (RTH) is a clinical syndrome defined by impaired sensitivity (TH). We present the challenges in diagnosing and treating 24-year-old male who presented with mixed picture of hypothyroidism hyperthyroidism elevated TSH, upper normal free T4, T3 was found have mutation THRβ gene. A referred for second opinion post-ablative T3, suspicion pituitary microadenoma. He comp...

OBJECTIVE To present two cases with thyrotropin-secreting adenoma and the effectiveness of octreotide acetate treatment on their tumor size as well as on thyroid stimulating hormone (TSH) and thyroid hormone levels. CASE REPORTS The first case presented with tremor, palpitations and sweating as suggestive of hyperthyroidism, but the other one presented with predominantly headache, while the o...

Despite the presence of large number and diverse populations of commensal microbes, gut mucosa has evolved to maintain “microbial-tolerance”, which is critically regulated by well-controlled Toll-like receptor (TLR) signaling. Deregulated TLR signaling has been linked to the pathogenesis of inflammatory bowel disease and colon cancer; however, the underlying mechanisms need to be further define...