نتایج جستجو برای: mf59

تعداد نتایج: 256  

2015
Sylvie Bertholet Rino Rappuoli Ennio De Gregorio Fabio Bagnoli Elisabetta Soldaini Donatello Laera Oretta Finco Sandra Simona Tavarini Chiara Sammicheli Silvia Rossi Paccani Rocco Cantisani Elisabetta Monaci Corrado Carrisi Giuseppe Lofano Francesca Mancini Giulia Salvatore Simona Tavarini Sandra Nuti

2011
Paul D Griffiths Anna Stanton Erin McCarrell Colette Smith Mohamed Osman Mark Harber Andrew Davenport Gareth Jones David C Wheeler James O'Beirne Douglas Thorburn David Patch Claire E Atkinson Sylvie Pichon Paul Sweny Marisa Lanzman Elizabeth Woodford Emily Rothwell Natasha Old Ruth Kinyanjui Tanzina Haque Sowsan Atabani Suzanne Luck Steven Prideaux Richard SB Milne Vincent C Emery Andrew K Burroughs

BACKGROUND Cytomegalovirus end-organ disease can be prevented by giving ganciclovir when viraemia is detected in allograft recipients. Values of viral load correlate with development of end-organ disease and are moderated by pre-existing natural immunity. Our aim was to determine whether vaccine-induced immunity could do likewise. METHODS We undertook a phase-2 randomised placebo controlled t...

2015
Diego Piccioli Carmine Malzone Ennio De Gregorio Ugo D'Oro Rocco Cantisani Alfredo Pezzicoli Rossella Cioncada Ugo D’Oro

2014
P Colombatto M R Brunetto A M Maina V Romagnoli P Almasio M G Rumi A Ascione G Pinzello M Mondelli L Muratori R Rappuoli D Rosa M Houghton S Abrignani F Bonino

Hepatitis C virus (HCV) vaccines may be able to increase viral clearance in combination with antiviral therapy. We analysed viral dynamics and HCV-specific immune response during retreatment for experienced patients in a phase Ib study with E1E2MF59 vaccine. Seventy-eight genotype 1a/1b patients [relapsers (30), partial responders (16) and nonresponders (32) to interferon-(IFN)/ribavirin-(RBV)]...

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