BACKGROUND Guidelines for assessing methodological and reporting quality of systematic reviews (SRs) were developed to contribute to implementing evidence-based health care and the reduction of research waste. As SRs assessing a cohort of SRs is becoming more prevalent in the literature and with the increased uptake of SR evidence for decision-making, methodological quality and standard of repo...

PURPOSE To determine the best treatment option for not complicated acute appendicitis (AA) in adult patients, between single incision laparoscopy (SIL) and conventional laparoscopy (CL), measured by morbidity associated with disease. METHODS Systematic review. Articles of adults diagnosed with AA treated by SIL or CL were analyzed. Databases included: MEDLINE, LILACS, IBECS, Web of Science, S...

We provide a taxonomy of the two most important debates in the philosophy of the cognitive and neural sciences. The first debate is over methodological individualism: is the object of the cognitive and neural sciences the brain, the whole animal, or the animal--environment system? The second is over explanatory style: should explanation in cognitive and neural science be reductionist-mechanisti...

A theoretical-methodological reflection on the relationship between Architecture and Urbanism, childhoods, basic education is presented here. Identifying possibility of from territory itself, in a transdisciplinary perspective that values te university outreach as something fundamental this process, observing school space with territorial educational potential. There also critique ways doing th...

iterative model-building behaviour which consists of dividing the morphology of the specimens into putative radiation sources evaluating the division and then re-dividing the morphology again as necessary. This approach, the full possibilities of which are yet to be fully explored, permits in favourable cases the localization of radioactivity to extremely small features within cells. In practic...

The article is devoted to the analysis of possibilities developing targeted programs and projects. interrelation program-target management method with other methods its implementation at regional level has been analyzed. When preparing projects, methodological errors are often made. In particular, goal solving problem requirements for achieving it not specifically formulated. This significantly...

To date, much of the work that uses Geographical Information Systems (GIS) to study human geographies applies a social science paradigm to quantitative data. There is a growing recognition of the need, however, to test whether GIS can be used to map out the qualitative ‘data’ provided by the articulation of subjective spatial experiences. This paper expands the conceptual possibilities opened u...

This issue is devoted to statistics applied to decision making problems. The issue begins from consideration of methodological possibilities to construct regressions with meaningful and interpretable coefficients for individual predictors and shares of their importance. Ewa Nowakowska explores properties of the so-called Shapley value regression developed for adjusting regression coefficients w...

............................................................................................................................................... 3 Introduction .......................................................................................................................................... 4 Overview of the main methodological approaches to SAE ..............................................

IMPORTANCE OF THE FIELD The past decade had witnessed remarkable advances in computer science which had given rise to many new possibilities including the ability to simulate and model life's phenomena. Among one of the greatest gifts computer science had contributed to drug discovery is the ability to predict the biological activity of compounds and in doing so drives new prospects and possibi...