The determination of antimicrobial susceptibility of a clinical isolate, especially with increasing resistance, is often crucial for the optimal antimicrobial therapy of infected patients. Nucleic acid-based assays for the detection of resistance may offer advantages over phenotypic assays. Examples are the detection of the methicillin resistance-encoding mecA gene in staphylococci, rifampin re...

objectives: staphylococcus aureus is an important cause of serious infection in both hospital and the community. methicillin-resistant s. aureus (mrsa) is associated with high morbidity and mortality rates with rapid development of resistance. there is a need for early and reliable detection of mrsa infection to direct antibiotic therapy, and more effectively control cross-infection. in this st...

Background & Aims: Staphylococcus aureus is one of the most common pathogens in nosocomial infections. Vancomycin is the most important therapeutic drug of choice for treatment of infections caused by methicillin-resistant Staphylococcus aureus (MRSA) strains. Therefore, vancomycin-resistant Staphylococcus aureus (VRSA) or vancomycin-intermediate Staphylococcus aureus (VISA) strains are warning...

OBJECTIVES Integrons are thought to play an important role in the spread of antibiotic resistance. This study investigates class 1 and 2 integron-positive methicillin-resistant coagulase-negative staphylococci strains isolated in Iran and characterizes their patterns of antimicrobial resistance. METHODS Hundred clinical isolates of coagulase-negative staphylococci were characterized for integ...

background methicillin-resistant staphylococcus aureus (mrsa) is considered a major cause of nosocomial and community infections. its prevalence varies from country to country, even between hospitals of a country. these bacteria often have multi-resistance and can be difficult to treat. objectives the current study evaluated the effect of hydroalcoholic extract of the stem bark of juglans regia...

background: methicillin-resistant staphylococcus aureus (mrsa) is resistant to most antibiotics and is an important pathogen of nosocomial infections. the prevalence of community (ca-mrsa) and hospital acquired methicillin-resistant s. aureus (ha-mrsa) infection is increased. in this study we investigated the frequency of mrsa colonization and its antibiotic susceptibility in students of rafsan...

background: macrolides, lincosamides and type b streptogramins (mlsb) are commonly used for the treatment of staphylococcal infections. inducible mlsb resistance (imlsb) cannot be identified by standard methods of antibiotic susceptibility testing. d-test appears to be a reliable indicator of imlsb strains. the aim of this study was to determine the prevalence of clindamycin resistance phenotyp...

Background: Pseudomonas aeruginosa is the primary cause of infection with impaired defense mechanisms. P. aeruginosa commonly causes nosocomial infections and is the most common pathogen isolated from patients hospitalized for longer than 1 week. We examined the antimicrobial effect of multilayered carbon nanotubes on multi-drug-resistant. Materials and methods: In this research, 20 clinical i...

The study objective was to determine the prevalence and risk factors for nasal colonization with Staphylococcus aureus and methicillin resistance among the urban poor and to compare antibiotic resistance and genetic similarity to concurrently collected clinical isolates of methicillin-resistant S. aureus (MRSA). A population-based community sample of 833 homeless and marginally housed adults we...