Different organic and aqueous extracts of leaves of Cassia occidentalis L (Caesalpiniaceae) were screened for their antimicrobial activity against seven human pathogenic bacterial and two fungal strains by disk diffusion assay. The pattern of inhibition varied with the solvent used for extraction and the microorganism tested. Among these extracts, methanol and aqueous extracts showed significan...

Aim of the study: To evaluate the antioxidant property of Smilax zeylanica L. using CCl4 hepatotoxicity in rats. Materials and methods: Hepatotoxicity was induced in Wistar albino rats by administration of CCl4 (0.5ml/kg/day p.o. for 7days). Methanol extract of S. zeylanica roots and rhizomes (SZRM) was administered to the experimental animals at doses 200,400 and 600 mg/kg/day, p.o. for 7 days...

A radioimmunoassay was developed to detect the cholecystokinin (CCK)-associated nonapeptide (CAP-9) that forms the COOH terminus of pig preproCCK. This peptide (Ser-Ala-Glu-Glu-Tyr-Glu-Tyr-Thr-Ser) is presumably produced at the time that the tyrosine-sulfated octapeptide CCK8(s) is cleaved from preproCCK. Radioimmunoassay of a dried methanol extract of pig brain revealed no detectable CAP-9 imm...

In this article, the effect of Nasturtium officinale (watercress, belonging to Brassicaceae) extracts on the blood glucose level was evaluated in diabetic rats. After inducing diabetes via streptozotocin injection, the animals were orally received various concentrations of N. officinale extracts (ethyl acetate, methanol and aqueous) for short (one week) and long (two months) periods. Only 800 a...

The methanol extract of the bark of Machilus odoratissima was subjected to investigate its antioxidant and antibacterial properties. The phytochemical screening demonstrated the presence of different types of compound like terpenoids, tannins, deoxy sugar, saponins and phenolic compounds. The methanol extract of the plant was tested for antioxidant activity using scavenging activity of DPPH(1,1...

The present paper deals with the antigenotoxic activity of Aegle marmelos fruit extracts employing short term assays i.e. the SOS chromotest using Escherichia coli PQ37 and the Comet assay in peripheral human blood lymphocytes. Methanol extract and Acetone extract were quite effective in decreasing the SOS response induced by hydrogen peroxide and aflatoxin B1 in the SOS chromotest. Methanol ex...

Agastachis Herba is one of the well-known medicinal herbs in Korean traditional medicine. This study was taken up to examine the beneficial effects of Agastachis Herba on a mice model of asthma. BALB/c mice were sensitized and challenged with ovalbumin to produce a murine model of asthma. Methanol extracts of Agastachis Herba were orally administered to the ovalbumin-induced asthmatic mice. The...

The phytochemical analysis of the polar extracts of Cedrus brevifolia needles yielded 20 compounds, namely from the methanol extract we isolated three flavonoids (1-3), one hydrolysable tannin (4), eleven phenolic derivatives (5-15) and one apocarotenoid (16), while from the methanol: water (5:1) extract we isolated four flavonoids (17-20). Chemical structures of all isolated compounds were det...

In recent years, oxidative stress and free radicals have been implicated in impaired wound healing. Abelmoschus manihot (L.) Medik., Malvaceae, and Wrightia tinctoria R. Br., Apocynaceae, plants widely used in Ayurveda, possesses anti-inflammatory and antimicrobial properties. The present study was undertaken to assess the potential of petroleum ether and methanol extracts in wound healing in W...

The present study describes the ethnobotanical, phytochemical, and toxicological evaluations of Xanthium strumarium L. growing in Bangladesh. In toxicity evaluation on rats, the methanol extract of seedlings showed mortality, while both seedling and mature plant extracts raised the serum alanine transaminase and aspartate transaminase values and produced significant abnormalities in the histopa...