based on findings of previous studies, those men on methadone maintenance therapy (mmt) have a high prevalence of erectile dysfunction(ed), related to hypogonadism and depression. we conducted this study to evaluate the efficacy of trazodone (an antidepressant which can improve sexual function) on this sexual dysfunction.a structured interview was administered by the clinical staff. the intervi...

BACKGROUND Psychoactive substance use can cause a broad variety of mental health disorders and social health problems for the drug users, their family and society. OBJECTIVES The Ministry of Health, Treatment, and Medical Education of Iran has recently proclaimed an estimated number of 2 million drug abusers and 200,000 injecting drug users (IDUs). PATIENTS AND METHODS For data collection, ...

BACKGROUND Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV) coinfection is a major global health problem especially among people who inject drugs (PWID), with significant clinical implications. Mathematical models have been used to great effect to shape HIV care, but few have been proposed for HIV/HCV. METHODS We constructed a deterministic compartmental ODE model that incorpora...

OBJECTIVES With the rise in methadone maintenance therapy (MMT) for drug users in Vietnam, there has been growing interest in understanding if and how often MMT patients engage in concurrent illicit drug use while on methadone therapy in various settings. This study examined factors associated with concurrent opioid use among patients on MMT in a mountainous area in Vietnam. SETTING One urban...

BACKGROUND This study aims to: (1) document the prevalence of hepatitis C virus (HCV) among methadone maintenance treatment (MMT) patients in Kunming and Shanghai; (2) examine risk factors for HCV by comparing those who tested positive with those who were negative and (3) examine if HCV serostatus is related to attitudes toward MMT. METHODS Using data collected from 306 patients admitted to M...

the ministry of health, treatment and medical education of iran has recently announced an estimated figure of 200,000 injecting drug users (idus). the aim of this study was to pilot a national program using demographics, types of drug abuse and prevalence of blood-borne infections among idus.in order to elicit data on demographics, types of drug abuse and prevalence of blood-borne infections am...

background: one of the major challenges in current methadone maintenance treatment retention rates in the treatment and prevention of relapse addiction. the aim of this study was determine the factors influencing relapse based on health belief model. methods: a cross-sectional study was conducted among 384 patients on methadone maintenance treatment referred to addiction clinic in hamadan, whic...

BACKGROUND We sought to assess injection practices, means of acquiring and disposing of syringes, and utilization and knowledge of harm reduction resources among injection drug users (IDUs) entering methadone maintenance treatment (MMT). METHODS Interviews with 100 consecutive patients, including 35 IDUs, entering a MMT program in the Bronx, NY. RESULTS Utilization of unsafe syringe sources...