Increased osteoclastogenesis and angiogenesis occur in physiologic and pathologic conditions. However, it is unclear if or how these processes are linked. To test the hypothesis that osteoclasts stimulate angiogenesis, we modulated osteoclast formation in fetal mouse metatarsal explants or in adult mice and determined the effect on angiogenesis. Suppression of osteoclast formation with osteopro...

BACKGROUND There are no unified theories as to the anatomical changes that occur with hallux valgus, we investigated the radiological characteristics and anatomical risk factors for hallux valgus deformity in Chinese adults. METHODS We reviewed 141 patients with hallux valgus (206 feet; 15 males, 126 females; mean age, 58.5 years). These patients attended Peking University People's Hospital f...

Endochondral ossification begins from the condensation and differentiation of mesenchymal cells into cartilage. The cartilage then goes through a program of cell proliferation, hypertrophic differentiation, calcification, apoptosis, and eventually is replaced by bone. Unlike most cartilage, articular cartilage is arrested before terminal hypertrophic differentiation. In this study, we showed th...

The aim of this study was to determine the prevalence fracture and risk variables connected its occurrence in calves cats at Veterinary Teaching Hospital, Bangladesh Agricultural University, Mymensingh. A total 96 (calves) 17 (cats) retrospective datasets were compiled between January 2015 December 2019. Age, sex, breed, season, involvement bone, type considered characterize fractures. To exami...

The oldest Giraffa material presently known consists of dental specimens. The oldest post-cranial Giraffa material belongs to the Plio-Pleistocene taxon Giraffa sivalensis, where the holotype is a third cervical vertebra. We describe three non-dental specimens from the Early Late Miocene of the Potwar Plateau, including an 8.1 million year old ossicone, 9.4 million year old astragalus, and 8.9 ...

This paper describes the method of measuring and assessing the pressure distribution under typical feet and the feet of patients with deformities such as: planovalgus, clubfoot, and pes planus using a pedobarograph. Foot pressure distribution was measured during static and walking at individual normal walking speed. Time-series pressure measurements for all sensors were grouped into five anatom...

The accessory bones of the foot have fascinated anatomists for five centuries. Andreas Vesalius in I 568 (published in I 725) was the first to draw attention to an accessory ossicle situated at the base of the fifth metatarsal bone, and much has been written subsequently about two distinct groups of accessory bones. In the first are those which are contained within the fibres of tendons and are...

Low-dose oral steroid therapies are very effective in active rheumatoid arthritis (RA), reducing disease activity in acute crisis either while waiting for disease-modifying antirheumatic drugs (DMARDs) to take effect or if it was slow in response to DMARDs. However, long-term steroid therapies are associated with serious side effects, such as osteoporotic reduction of bone mass and frequent fra...