Persistent spectral hole burning is studied for several free-based and metallo-naphthalocyanine derivatives in polymer hosts. These materials exhibit a strong 0}0 absorption band in the region 800 nm matching the wavelength range of most semiconductor diode lasers and Ti : Sapphire lasers. Metallo-naphthalocyanines demonstrate a nonphotochemical hole-burning mechanism that is likely related to ...

This study shows for the first time the mechanism of carbapenem resistance of a Klebsiella pneumoniae clinical isolate TJ8 recovered from Tianjin Medical University General Hospital ,China. The modified Hodge test and EDTA synergy test were performed for the screening of carbapenemases and metallo-β-lactamases (MBLs), respectively. Polymerase chain reactions and DNA sequencing confirmed that th...

As part of the SENTRY Antimicrobial Surveillance Program, an imipenem-resistant Pseudomonas aeruginosa strain (81-11963A) was isolated from the blood culture of a female neonate institutionalized at the local children's hospital in Warsaw, Poland. Cloning of an imipenem resistance determinant revealed it to be a VIM-2 metallo-beta-lactamase, but sequence analysis of DNA adjacent to blaVIM-2 rev...

The 1D polymeric Schiff base zinc complex, [LZn(2)Et(2)](n), where LH(2) = (NN'-ethylene-bis(4-iminopentan-2-one)) has been demonstrated as a useful synthetic metallo building block for the synthesis of homo and heteronuclear zinc cages. The reaction of [LZn(2)Et(2)](n) with CdI(2) afforded the hetero-nuclear cage, 1, [L(2)Zn(4)(Et)(2)CdI(4)], while reaction with HgI(2) afforded a hexanuclear z...

In modern society transition metal catalysis plays an important role in a wide variety of chemical transformations. In the context of sustainable chemistry it is desirable to move from precious metals (such as palladium, platinum, iridium, etc.) to base metal catalysts (cobalt, iron, manganese, etc.), which are found in natural metallo-enzymes. These complexes mainly react through one-electron ...

Organometallic pyridocarbazole scaffolds are investigated as protein kinase inhibitors. Whereas our previous designs employed solely a maleimide pharmacophore for achieving the two crucial canonical hydrogen bonds to the hinge region of the ATP binding site, we have now extended our investigations to include the related lactam metallo-pyridocarbazoles. The synthetic access of the two regioisome...

Two metallo-proteinases of human neutrophil leucocytes, collagenase and gelatinase, were studied. Collagenase specifically cleaved native collagen into the TCA and TCB fragments, whereas gelatinase degraded denatured collagen, i.e. gelatin, and the TCA fragments produced by collagenase. On subcellular fractionation by zonal sedimentation, collagenase was found to be localized in the specific gr...

INTRODUCTION This study set out to investigate the molecular epidemiology of carbapenemase-producing Enterobacteriaceae isolates collected from Xiang Ya Hospital, Hunan, China. METHODOLOGY The carbapenemase genes from Enterobacteriaceae isolates were determined by PCR and sequencing. Relatedness of Klebsiella pneumoniae isolates was evaluated by pulsed-field gel electrophoresis. RESULTS Twe...

background and objectives : the rapid emergence and dissemination of carbapenemase-producing klebsiella pneumoniae strains and other members of the enterobacteriaceae poses a considerable threat to the care of hospitalized patients and to public health. the aim of this study was to determine the frequency of metallo-β-lactamases (mbl) and vim-1 gene in multidrug-resistant strains of k. pneumoni...

We introduce thermal metallo-dielectric metasurfaces as mid IR sources. The emitter is a lossy metal. spectral and angular emission controlled using periodic array of high refractive dielectric resonators. design that allows to control independently the bandwidth aperture while ensuring large emissivity. To validate concept, we fabricated characterized metasurface, showing good agreement with t...